年龄和维生素D状态对绝经后女性骨质疏松患者握力的影响
The effect of age and vitamin D status on the hand grip strength in the postmenopausal osteoporotic women
  
DOI:10.3969/j.issn.1006.7108.2017.03.007
中文关键词:  年龄  维生素D  握力  骨质疏松  骨质疏松  绝经后
英文关键词:Age  Vitamin D  Hand grip strength  Osteoporosis  Osteoporosis, Postmenopausal
基金项目:福建省医药卫生科技创新项目(2015CXB18);福建省泉州市科技项目(2014Z44)
作者单位
李毅中1* 庄华烽1 林长堃1 蔡思清2 1.福建医科大学附属第二医院骨科福建 泉州362000 2.福建医科大学附属第二医院放射科福建 泉州362000 
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中文摘要:
      目的 观察年龄和维生素D状态对绝经后女性骨质疏松患者握力的影响。方法 对123例绝经后女性骨质疏松患者进行血清25(OH)D检测和手握力测量,25(OH)D检测采用电化学发光法。手掘力测量使用手持式Jamar 测力计,取优势侧握力最大值作为分析数据:观察患者年龄与最大握力的相关性和患者年龄与血清25(OH)D的相关性,研究血清25(OH)D 与最大握力的相关性,结果 年龄44?91岁,平均(65. 55 ±10. 66)岁。最大握力6?34 kg,平均(22. 24 士 6. 05) kg,年龄与最大握力呈显著负相关;25(OH)D为6. 32?52. 23 ng/ml,平均(24. 35 ±8. 23)ng/inl,年龄与血清25(OH)D呈显著负相关,25 (OH)D与最大握力无显著相关性,当25(OH)D≤10 ng/ml时,最大握力显著降低。结论 在绝经后骨质疏松女性中,年龄是导致握力和25(OH)D水平下降的重要因素,维生素D缺乏时可致握力下降。
英文摘要:
      Objective To study the effect of age and vitamin D status on the hand grip strength in the postmenopausal osteoporotic women. Methods The serum 25(OH)D and hand grip strength were measured in 123 postmenopausal women with osteoporosis. 25 ( OH) D measurement was performed with the electrochemiluminescence immunoassay. Hand grip strength measurement was performed using a handheld Jamar dynamometer and the maximum grip strength of the advantage side was used for data analysis. The correlation between age and 25 (OH) D, and between 25 (OH) D and maximum grip strength was studied. Results The patients were 44-91 years old, with an average of 65. 55 ± 10. 66 yrs. The maximum grip strength was 6-34 kg, with an average of 22. 24±6. 05 kg. Age had significant negative correlation with the maximum grip strength. 25( OH) D was 6. 32 -52. 23 ng/ml, with an average of 24. 35 ±8.23 ng/ml. Age had significant negative correlation with 25(OH) D. There was no significant correlation between 25( OH)D and the maximum grip strength. But the maximum grip strength significantly reduced in cases of 25( OH)D≤ 10 ng/ml. Conclusion Age is an important factor of the decrease in maximum grip strength and 25(OH)D in postmenopausal osteoporotic women. The decrease in maximum grip strength is present in cases of vitamin D deficiency.
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