| Osteoporosis is a systemic metabolic bone disease characterized by low bone mass, destruction of bone microstructure, increased bone frailty and increased fracture risk, which can have severe influence on the patient’s quality of life. With the ageing of the Chinese population, osteoporosis in the elderly and its relevant treatment have received more and more attention. Application of traditional Chinese medicine in the treatment of osteoporosis has significant clinical efficacy，but the clinical adverse reactions are also common, and should be fully acknowledged. In this article, through searching CNKI, wanfang data info site, VIP, such as literature retrieval system, we summarized the common adverse reactions of traditional Chinese medicine in the treatment of osteoporosis in recent years. Using the theory of traditional Chinese medicine knowledge and modern TCM research method, we objectively analyzed the causes of adverse reactions from the prospects of clinical syndrome differentiation, overall medicinal properties, formulation dose and course of treatment, etc. Combined with the solutions suggested by some domestic experts, we also put forward some measures to actively cope with adverse drug reactions, in order to provide reference for clinical application and new drug development. |