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| 原发性骨质疏松症血瘀与疼痛的关系研究 |
| The relationship between blood stasis and pain in patients with primary osteoporosis |
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| DOI：10.3969/j.issn.1006.7108.2017.06.011 |
| 中文关键词: 原发性骨质疏松症 血瘀量化评分 血细胞参数 骨质疏松性疼痛 |
| 英文关键词:Primary osteoporosis Blood stasis quantization score Blood cell parameters Osteoporotic pain |
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| 中文摘要: |
| 目的 分析原发性骨质疏松症患者血瘀与骨质疏松性疼痛的关系。方法 收集2014年6月至2015年10月广州中医药大学第一附属医院确诊为原发性骨质疏松症血瘀证患者99例，检测患者腰椎骨密度及血细胞参数（MCV、RDW-CV、MPV、PDW)水平,并对所有患者进行血瘀评分及疼痛评分。结果 患者疼痛评分、血瘀评分随着年龄增高而呈不断升高的趋势，且疼痛评分与血瘀评分之间存在中度正相关（r=0.535,P<0.01);与RDW-CV呈低度正相关（r = 0. 357，P < 0. 01 )。结论原发性骨质疏松症患者骨质疏松性疼痛与血瘀存在一定的相关性，血瘀越严重，疼痛程度也越严重，提示血瘀在骨质疏松性疼痛致病机制中起着重要作用。 |
| 英文摘要: |
| Objective To evaluate the relationship between blood stasis and pain in patients with primary osteoporosis. Methods Data of 99 patients who were diagnosed primary osteoporosis-blood stasis syndrome at the First Affiliated Hospital of Guangzhou University of Chinese Medicine from June 2014 to October 2015 were collected. Patient's lumbar spine bone mineral density, blood stasis quantization score, visual analogue pain scale and levels of blood cell parameters ( MCV, RDW-CV, MPV and PDW) were assessed. Pearson correlation analysis was used to evaluate the relationships of visual analogue pain scale with blood cell parameters and blood stasis quantization score. Results Visual analogue pain scale and blood stasis quantization score increased with the increase of patient’s age. There was a moderate positive correlation between visual analogue pain scale and blood stasis quantization score( r =0. 535 ,P <0. 01). There was a weak positive correlation between visual analogue pain scale and RDW-CV ( r = 0. 357 ,P <0.01). Conclusion There was certain degree of correlation between blood stasis and pain in patients with primary osteoporosis，such that visual analogue pain scale increased with the increase of blood stasis quantization score，which suggests that blood stasis plays an important role in the pathogenesis of pain in patients with primary osteoporosis. |
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