| Objective To observe and analyze the efficacy of parathyroid hormone combined with puerarin for the treatment of osteoporotic femoral trochanteric fracture in elderly patients, and to explore a safe, reliable, and more effective treatment plan. Methods 88 cases of femoral trochanteric fractures were treated from January 2013 to January 2015. They were divided into treatment group and control group by random number table method, with 44 cases in each group. Both groups were treated with PFNA. After surgical treatment, the patients from treatment group were treated with parathyroid hormone combined with puerarin, and the control group received puerarin treatment. The visual analogue pain scores (VAS), hip function scores (Harris), fracture healing time and bone mineral density (BMD) of femoral neck and lumbar spine were compared between the two groups. Results: The VAS scores of the two groups significantly decreased at 1 week, 3 month and 6 months after operation, and the score of the treatment group was significantly lower than that of the control group (P<0.05). The Harris scores of both groups increased significantly at 3 and 6 months after operation, and the score of the treatment group was significantly higher than that of the control group (P<0.05). The time of fracture healing in the treatment group was significantly shorter than that in the control group (P<0.05). At 3 and 6 months after operation, BMD of femoral neck and lumbar spine in the treatment group significantly improved (P <0.05), while there were no significant changes in patients in the control group before and after treatment (P＞0.05). Conclusion Parathyroid hormone combined with puerarin can significantly increase osteoporotic fracture healing in the elderly, and improve the prognosis of treatment. |