|
| 应用FRAX工具评估类风湿关节炎患者骨折风险及其风险因素的相关性研究 |
| Application of FRAX tool to evaluate fracture risk and the risk factors in patients with rheumatoid arthritis |
| |
| DOI：10.3969/j.issn.1006.7108.2017.09.008 |
| 中文关键词: 骨质疏松 骨密度 类风湿关节炎 |
| 英文关键词:Osteoporosis Bone mineral density Rheumatoid arthritis |
| 基金项目: |
|
| 摘要点击次数: 819 |
| 全文下载次数: 581 |
| 中文摘要: |
| 目的 探讨骨折风险评估工具（FRAX）预测类风湿关节炎（RA）患者骨质疏松性骨折的临床应用价值并对其骨折风险因素进行相关性分析。方法 回顾性分析2015年1月至2016年2月期间经确诊的74例类风湿关节炎患者以及正常对照组76例的相关临床指标以及骨密度值；评估FRAX对类风湿关节炎患者的骨折风险预测值以及FRAX与类风湿临床风险因素之间的关系。结果 类风湿组股骨颈、腰椎的骨密度值均低于对照组，而类风湿组中10年主要骨质疏松性骨折发生概率和10年髋部骨折发生概率均高于对照组。多重线性回归分析提示FRAX评分与易激动、口味偏淡、体重指数、S-CTX具有一定的相关性。结论 FRAX工具对临床评估RA患者骨质疏松性骨折风险、预后评价等方面具有良好的应用价值。 |
| 英文摘要: |
| Objective To study the prediction value of osteoporotic fractures in patients of rheumatoid arthritis (RA) with fracture risk assessment tool (FRAX) and to analyze the correlation with fracture risk factors. Methods Retrospective analysis of clinical parameters and bone mineral density was performed in 74 patients with rheumatoid arthritis and 76 normal cases in control group from January 2015 to February 2016. The ability of prediction fracture in RA patients with FRAX was assessed and the relationship between the clinical risk factors and value of FRAX was analyzed. Results BMD of the femoral neck and lumbar spine in RA group was lower than that in the control group. The 10-year primary osteoporosis fracture probability and 10-year hip fracture probability in RA group were higher than those in the control group. Multiple linear regression analysis revealed that FRAX value had a certain relevance with excitability, partial light taste, body mass index, and S-CTX. Conclusion FRAX tool has a good application value for evaluation fracture risk and prognosis of RA patients with osteoporosis. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |