| Objective To identify the related factors of osteoporosis in breast cancer women 1-year after the surgery. Methods Forty-one breast cancer patients 1-year after surgery aged from 53 to 75 years old with osteoporosis were selected. Fifty-six breast cancer patients 1-year after surgery aged from 46 to 64 years old with normal bone mineral density (BMD) were selected in the control group. BMD of the lumbar spine and the left femoral neck was detected using dual-energy X-ray absorptiometry (GE, USA). The correlation analysis among age, BMI, reproductive history, postmenopausal time, ER, PR, HER-2, and BMD was performed. Results There was significant difference in age, BMI, and postmenopausal time between OP group and NOP group (P<0.05). However, there was no difference in ER, PR, HER-2, and reproductive history between the two groups (P>0.05). Correlation analysis indicated that BMD was positively correlated with BMI, but was negatively correlated with age and postmenopausal time. Conclusion The prevalence of osteoporosis in women with breast cancer is high. The main influential factors are age, BMI, and postmenopausal time. |