| Uric acid is the end product of purine metabolism. It is also an important endogenous antioxidant in the body and plays an important role in oxidative stress, which is an independent risk factor for osteoporosis. Therefore, there may be some correlations between serum uric acid and bone loss. In recent years, there are many researches on the correlations between serum uric acid and bone mineral density in both China and overseas, but the exact relationship is still controversial. This paper mainly elaborates the relationship between serum uric acid and bone mineral density in different populations, the possible mechanisms, and the controversy on their correlation, etc., in order to deepen the understanding of the two and to provide new ideas for research on clinical management. |