| Objective To evaluate the efficacy of combined use of traditional Chinese and western medicine in combination with conservative treatment in elderly patients with osteoporotic proximal humerus fractures. Methods 100 patients with osteoporotic proximal humerus fractures were randomly divided into treatment group (n=50) and control group (n=50). All patients were given a manual reduction combined with an adjustable upper limb extubation treatment. The treatment group additionally received alendronate sodium combined with Xianlinggubao treatment for 12 months. Healing time, complication, bone metabolism and bone mineral density were compared before and after treatment. Results 1, 3, 6 and 12 months after treatment, the scores of NRS in the treatment group were significantly lower than those in the control group (P<0.05), and the shoulder function was significantly better in the treatment group than that the control group at 12 months (P<0.05). The incidence of postoperative complications in the treatment group was significantly lower than that in the control group (P<0.05), and the time of fracture healing was significantly shorter in the treatment group than that in the control group (P<0.05). After treatment for 6 and 12 months, BMD of the lumbar spine (L2-4), left femoral neck and serum BGP were significantly higher in the treatment group than in the control group, while the level of serum β-CTX in the treatment group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in serum N-MID level between the two groups before and after treatment (P>0.05). Conclusion Alendronate combined with Xianlinggubao was safe and effective in the treatment of osteoporotic proximal humerus fractures in elderly patients. It could effectively relieve pain, accelerate fracture healing, improve the shoulder function of patients and reduce the complications incidence after treatment, thus is worthy of clinical promotion. |