| Objective To analyze the difference of dynamic balance index among diverse 25-hydroxyvitamin D level groups in patients with type 2 diabetes mellitus, and to investigate the relationship between 25-hydroxyvitamin D and dynamic balance. Methods Two handred and thirty-five inpatients from 08/2016 to 06/2017 with type 2 diabetes were enrolled, aged from 30 to 80 years old. Height ,weight, waistline, blood pressure, fasting blood glucose, HbA1c, 25-hydroxyvitamin D levels, calcaneal bone mineral density (CBMD), ABI and vibration sensory threshold of lower limbs were measured. The dynamic balance were assessed with chair-rising test(CRT),tandem gait test(TGT), 8-foot (ie,2.4 m) walk test. The patients were divided into 4 groups by the level of 25-hydroxyvitamin D: Serious deficiency group, deficiency group, insufficiency group, sufficiency group.Results There were no significantly difficiency of age, Fasting blood glucose, HbA1c, Systolic blood pressure, waistline, BMI between the four groups. The CBMD in Serious deficiency group was significantly lower than deficiency group ,insufficiency group and suffciency group（P＜0.05）. The ABI in serious deficiency group was significantly lower than deficiency group ,insufficiency group and suffciency group（P＜0.05). The ABI in deficiency group was also significantly lower than insufficiency group and suffciency group（P＜0.05). The vibration sensory threshold of lower limbs in serious deficiency group and deficiency group was significantly lower than insufficiency group and suffciency group（P＜0.05).The time of chair-rising test in Serious deficiency group was significantly extender than those in deficiency group , insufficiency group and sufficiency group. The time of chair-rising test in deficiency group was significantly extender than those in insufficiency group and sufficiency group. The time of 8-foot (ie,2.4 m) walk test in Serious deficiency group was significantly extender than those in deficiency group, insufficiency group and sufficiency group. The ability to perform tandem gait test(TGT) in Serious deficiency group is significantly lower than those in deficiency group , insufficiency group and sufficiency group（P＜0.05）. Multiple stepwise regression analysis showed that the time of chair-rising test and 8-foot (ie,2.4 m) walk test were independent influencing factors of the level of 25-hydroxyvitamin D.Logistic regression analysis showed that tandem gait test were positive correlated with the level of 25-hydroxyvitamin D. Conclusion There is independent negative correlation between the level of 25-hydroxyvitamin D and the time of chair-rising test and 8-foot walk test . There is independent positive correlation between the level of 25-hydroxyvitamin D and tandem gait test .The screening and supplement of vitamin D in patients with type 2 diabetes mellitus still needs further research. |