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| 结合力生长因子探讨骨肉不相亲理论与骨质疏松症 |
| The association between the theory of disharmony between bone and muscle and osteoporosis in the view of mechanical growth factor |
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| DOI：10.3969/j.issn.1006.7108.2018.03.023 |
| 中文关键词: 骨肉不相亲 骨质疏松 机械应力 力生长因子 分子机制 |
| 英文关键词:Disharmony between bone and muscle Osteoporosis Mechanical stress Mechanical growth factor Molecular mechanism |
| 基金项目:甘肃省自然科学基金计划（1506RJZA048）；甘肃省中药现代制造工程研究院项目（YWW-2015049）；甘肃省中医药防治慢性疾病重点实验室开放基金项目（GSMBKY2015-07）；甘肃省财政厅基本科研业务课题（BH2010-428）；甘肃省中医药管理局科研课题(GZK-2016-17)；甘肃中医药大学研究生创新基金（CX2017-06） |
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| 中文摘要: |
| 骨肉不相亲理论是中医学的经典理论，本文基于骨肉不相亲理论，由骨骼肌的机械应力刺激引出力生长因子，从分子生物学的角度论述了骨肉不相亲理论的科学内涵，进一步探讨了骨骼与肌肉的关系，并解释完善了运用骨肉不相亲理论防治骨质疏松症的作用机制，为中医药防治骨质疏松症提供了理论依据。 |
| 英文摘要: |
| The theory of disharmony between bone and muscle is a classical theory of traditional Chinese medicine. Based on this theory, this paper draws mechanical growth factor from the mechanical stress stimulation of skeletal muscle and discusses the scientific connotation of this theory from the view of molecular biology. The paper further explores the relationship between the bone and muscle and explains the mechanism of prevention and treatment of osteoporosis using this theory, and provides a theoretical basis for prevention and treatment of osteoporosis with Chinese medicine. |
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