老年股骨转子间骨折患者下肢深静脉血栓形成与血流动力学指标的相关性
Correlation between deep venous thrombosis and hemodynamic indexes in the elderly patients with intertrochanteric fractures
  
DOI:10.3969/j.issn.1006.7108.2018.07.007
中文关键词:  老年人  股骨转子间骨折  下肢深静脉血栓形成  血流动力学  相关性
英文关键词:Elderly  Intertrochanteric fracture  Deep venous thrombosis of the lower extremities  Hemodynamics  Correlation
基金项目:2016年院级基金项目(2016JJXM080)
作者单位
刘顺贵* 陈子秋 刘义 王波 十堰市太和医院(湖北医药学院附属医院)骨五科湖北 十堰 442000 
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中文摘要:
      目的 探讨老年股骨转子间骨折患者下肢深静脉血栓(deep venous thrombosis,DVT)与血流动力学指标的相关性。方法 采用回顾性、抽样研究方法,2014年2月至2017年选择在我院诊治的老年股骨转子间骨折患者172例作为研究对象,根据DVT发生情况分为DVT组40例与非DVT组132例,记录两组的血流动力学、血液流变学特征并进行相关性分析。结果 DVT组的DVT发生于深静脉10例,股静脉20例,髂骨静脉10例。DVT组的股静脉管径、腘静脉管径的宽度显著大于非DVT组,DVT组的股静脉流速、腘静脉流速显著低于非DVT组;DVT组的全血低切黏度、全血高切黏度、全血中切黏度与FIB均显著高于非DVT组;DVT组的MAP与CVP值显著低于非DVT组,HR值显著高于非DVT组,对比差异都有统计学意义(P<0.05)。非条件Logistic回归法分析显示股静脉流速、腘静脉流速为导致DVT的主要危险因素(P<0.05);Pearson相关分析显示DVT患者的股静脉流速、腘静脉流速与全血低切黏度、全血高切黏度、全血中切黏度、FIB、MAP与CVP都有显著相关性(P<0.05)。结论 老年股骨转子间骨折患者DVT与血流动力学指标有显著相关性,超声检查与血液流变学指标检测可成为临床防御DVT的有效手段。
英文摘要:
      Objective To investigate the correlation between deep venous thrombosis(DVT) and hemodynamic indexes in the elderly patients with intertrochanteric fracture. Methods A total of 172 elderly patients with intertrochanteric fracture diagnosed and treated in our hospital were selected using a retrospective sampling method from February 2014 to 2017.All the patients were divided into DVT group (n=40) and non DVT group (n=132) accorded to the occurrence of DVT. The hemodynamic and blood rheology indexes in the two groups were recorded and the correlation was analyzed. Results DVT occurred 10 in deep vein, 20 in femoral vein, and 10 in iliac vein in the DVT group. The femoral vein diameter and popliteal vein diameter width in the DVT group were significantly larger than those in non DVT group. The femoral vein and popliteal vein flow velocity were significantly lower than those in non DVT group. The low shear blood viscosity, whole blood viscosity, and FIB were significantly higher than those in non DVT group. MAP and CVP in DVT group were significantly lower than those in non DVT group. HR was significantly higher than that in non DVT group. The differences compared were all statistically significant (P<0.05). Non-conditional logistic regression analysis showed that the femoral vein and popliteal vein flow velocity were the main risk factors of DVT (P<0.05). Pearson correlation analysis showed that femoral vein and popliteal vein flow velocity in DVT patients were significant correlation to low blood viscosity, whole blood viscosity, FIB, MAP, and CVP (P<0.05). Conclusion There is significant correlation between DVT and hemodynamic indexes in elderly patients with intertrochanteric fractures. The use of ultrasonography and hemorheology can be effective ways to prevent DVT.
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