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| 益气温经方联合新编五禽戏对绝经后骨量减低患者的临床疗效观察 |
| Clinical efficacy of classic formula, tonifying Qi and warming meridian, combined with modified 5-bird exercise on postmenopausal osteopenia patients |
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| DOI：10.3969/j.issn.1006.7108.2018.07.024 |
| 中文关键词: 中医中药 绝经后骨量减低 益气温经方 新编五禽戏 临床疗效 |
| 英文关键词:Traditional Chinese medicine Postmenopausal osteopenia Tonifying Qi and warming meridian formula Modified 5-bird exercise Clinical efficacy |
| 基金项目:2013年国家中医药管理局中医药行业科研专项项目（201307010） |
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| 中文摘要: |
| 目的 观察益气温经方联合新编五禽戏的综合疗法对绝经后骨量减低患者的临床疗效。方法 将120例绝经后骨量减低患者随机分为治疗组和对照组，每组60例。对照组患者予日光浴和饮食干预。治疗组患者在对照组的基础上予益气温经方联合新编五禽戏的综合疗法进行干预治疗。观察周期为12个月。观察两组患者治疗前、治疗6个月后、12个月后的腰椎骨密度(bone mineral denisty，BMD)、SF-36生活质量（SF-36 quality of life score，SF-36）评分，并统计治疗结束后两组患者骨质疏松症发生率。结果 ①腰椎骨密度: 治疗前，两组患者腰椎骨密度之间差异无统计学意义（P>0.05）；治疗后，治疗组患者腰椎骨密度逐渐升高，对照组患者腰椎骨密度呈下降趋势，治疗组与对照组患者治疗6个月后及治疗12个月后，两组腰椎骨密度值之间差异有统计学意义(P<0.05)；②骨质疏松发生率：治疗12个月后，治疗组有5例（10.0%）患者继发为骨质疏松症，对照组有13例(25.0%)患者继发为骨质疏松症，两组差异有统计学意义(P<0.05)。③SF-36生活质量评分：治疗前2组患者生活质量评分比较无统计学意义(P>0.05)。治疗12个月后，治疗组患者的生活质量评分明显高于对照组，两组差异有统计学意义(P<0.05)。结论 益气温经方联合新编五禽戏的综合疗法能够改善绝经后骨量减低患者生活质量，提升骨密度，降低骨质疏松的发生率，值得临床借鉴和应用。 |
| 英文摘要: |
| Objective To observe the clinical effect of classic formula, tonifying Qi and warming meridian, combined with modified 5-bird exercise on postmenopausal osteopenia patients. Methods One hundred and twenty postmenopausal osteopenia patients were randomly divided into treatment group and control group, with 60 cases in each group. The patients in the control group were treated with sun bath and diet intervention. On the basis of the control group, patients in the control group were treated with the classic formula, tonifying Qi and warming meridian, combined with modified 5-bird exercise. The observation period lasted for 12 months. Bone mineral density (BMD) of the lumbar vertebrae and the SF-36 quality of life score (SF-36) were examined before and 6 and 12 months after the treatment in both groups. The incidence of osteoporosis was analyzed after the treatment. Results (1) BMD of the lumbar vertebrae: there was no significant difference between the two groups before the treatment(P>0.05). After the treatment, it increased gradually in the treatment group, but decreased in the control group. There was significant difference in BMD of the lumbar vertebrae between the two groups at 6 months and 12months (P<0.05). There was significant difference in BMD of the lumbar vertebrae within the treatment groups after the treatment (P<0.05). (2) The Incidence of osteoporosis: After12 months, 5 patients (10.0%) in the treatment group and 13 patients (25.0%) in the control group were diagnosed with osteoporosis, and there was significant difference between the two groups (P<0.05). (3) SF-36 quality of life score: there was no significant difference in the result of SF-36 between the two groups before the treatment(P>0.05). After 12 months, SF-36 score in the treatment group was obvious higher than that in the control group, and there was a significant difference between the two groups (P<0.05). Conclusion The combined therapy of tonifying Qi and warming meridian formula and modified 5-bird exercise effectively improves the quality of life in patients with postmenopausal bone loss, increases BMD, and reduces the incidence of osteoporosis, which is worthy of clinical reference and application. |
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