“治未病”思想在预防骨质疏松性骨折的应用研究进展
Research progress on the clinical application of the idea of preventive treatment of a disease in the prevention of osteoporotic fractures
  
DOI:10.3969/j.issn.1006.7108.2018.09.022
中文关键词:  “治未病”思想  骨质疏松  骨折  预防  综述
英文关键词:idea of preventive treatment of a disease  osteoporosis  fracture  prevention  review
基金项目:国家自然科学基金:基于RS-fMRI及ERK-CREB-BDNF信号通路杜仲腰痛丸干预腰椎间盘突出症慢性疼痛的脑机制研究(81760877)②卫生部医药卫生科技发展研究中心科研基金:应用高粘度骨水泥(或骨水泥高粘度期)治疗椎体压缩性骨折引起的疼痛的临床研究(W2014ZT210)③国家中医药管理局国家中医临床研究基地业务建设科研专项课题:中医综合疗法对预防不同体质的绝经后妇女骨质疏松性椎体骨折的临床观察(JDZX2015039)
作者单位
马同 赵继荣2* 邓强2 陈祁青2 张海清2 赵宁2 赵生鑫1 薛旭1 郭培尧1 1.甘肃中医药大学 兰州 730000 2.甘肃省中医院 兰州 730050 
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中文摘要:
      骨质疏松性骨折(OPF)作为骨质疏松症(OP)最严重的并发症之一,严重影响中老年患者的健康及生活质量。中医“治未病”思想是疾病防治的重要指导思想,该思想与现代预防医学理念相结合、与现代医学发展成果骨折预测工具 、OP及OPF分子生物学机制相关信号通路等成果相补充,对骨质疏松性骨折的防治有深远意义。本文基于“治未病”思想中医渊源及骨质疏松性骨折生理、病理特点,结合现代医学骨质疏松性骨折预防工具及分子生物学机制相关信号通路等研究成果进行综述,探究“治未病”思想在骨质疏松性骨折中的防治意义,提高人们对OPF预防的重视程度,努力实现“防患于未然,治病于萌芽”的伟大目标。
英文摘要:
      Osteoporotic fracture, one of the most serious complications of osteoporosis, seriously affects the health and quality of life in middle-aged and elderly patients. The idea of preventive treatment of a disease in traditional Chinese medicine is an important guiding ideology for disease prevention and control. This idea combines with the modern preventive medicine concept, the achievements of modern medical development in fracture prediction, and molecular biological mechanisms in signal pathways. It has deep significance in the prevention of osteoporotic fractures. This paper reviews based on the theory of preventive treatment of a disease, the origin of traditional Chinese medicine and the physiological and pathological characteristics of osteoporotic fractures, combined with the modern medical osteoporotic fracture prevention instruments and molecular biological mechanisms related signal pathways and other research results. To explore the prevention and cure strategies of preventive treatment of a disease in the treatment of osteoporotic fracture, to improve people's awareness to osteoporotic fracture prevention, and to realize the great goal of prevention and cure from the bud.
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