维生素D对肌少症的影响及其作用
The effect and influence of vitamin D on Sarcopenia
  
DOI:10.3969/j.issn.1006.7108.2018.09.024
中文关键词:  维生素D,肌肉信号,肌少症
英文关键词:vitamin D  muscle signal  sarcopenia
基金项目:国家自然科学基金资助项目(81602864)
作者单位
姜宇 宣文华 任天丽* 南京医科大学附属无锡市第二人民医院风湿科江苏 无锡 214002 
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中文摘要:
      肌少症作为一种在老年人中发病率较高的综合征,日益受到人们的广泛关注,但是目前它的发病机制及治疗措施尚未达成共识。本文围绕维生素D与肌少症的相关性入手,探讨维生素D对于肌肉系统的病理生理作用,维生素D与肌肉细胞生长与衰退的关系,维生素D对肌肉的信号调控及功能的影响。初步阐述了维生素D对于肌少症的影响和作用,对于肌少症的防治提供新的临床思路。
英文摘要:
      Sarcopenia is a syndrome with high incidence in the elderly people. However, most of its pathogenesis and treatment have not been agreed. This paper focuses on correlation between vitamin D and sarcopenia. The discussion includes pathological and physiological role of vitamin D on bone muscle system, and the growth and degradation of muscle cells with related signal factor. The effect and influence of vitamin D on sarcopenia are discussed, providing a new clinical thinking for the prevention of sarcopenia.
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