妊娠期股骨头坏死病因机制研究进展
Research progress on the mechanism of pregnancy induced osteonecrosis of the femoral head
  
DOI:10.3969/j.issn.1006-7108.2018.10.020
中文关键词:  妊娠  股骨头坏死  病因机制
英文关键词:pregnancy  femur head necrosis  pathogenesis
基金项目:国家自然科学基金(81560782)
作者单位
周明旺1 刘一飞2 李盛华1* 付志斌1 邓昶2 陈彦同2 1.甘肃省中医院甘肃 兰州 730050 2.甘肃中医药大学甘肃 兰州 730000 
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中文摘要:
      股骨头坏死(osteonecrosis of the femoral head,ONFH)是一种常见的骨科疑难病,因致残率高,故有不死癌症之称。近年来,该病发病率不断上升,其防治已成为现代医学研究的热点。妊娠期股骨头坏死是一种特殊类型的股骨头坏死,逐渐被人们所关注。其发病人群特殊、发病机制复杂、易误诊漏诊,而妇女妊娠被认为与其发生密切相关,故笔者结合国内外最新研究情况,对妊娠期股骨头坏死病因及发病机制进行综述,以期为该病的临床防治提供指导。
英文摘要:
      Osteonecrosis of the femoral head (ONFH) is a common orthopaedic disease, which is known as the “undead cancer” because of its high disability rate. In recent years, the incidence of this disease has been increasing, and its prevention and treatment has become a hot topic in modern medical research. The pregnancy induced osteonecrosis of the femoral head is a special type of femoral head necrosis, which is gradually receiving more attention. Due to the special population of patients, its pathogenesis is complicated and it is easy to be misdiagnosed. Usually pregnancy is thought to be closely related to its occurrence. Therefore, combining the latest research situation in China and overseas, this review summarizes the etiology and pathogenesis of femoral head osteonecrosis in pregnancy, with the aim of providing guidance for the clinical prevention and treatment of ONFH.
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