中国骨质疏松杂志

加压结合抗阻训练对糖耐量减低人群骨密度、胰岛素敏感性、肌力、激素分泌影响研究

Effects of KAATSU and resistance training on bone mineral density，insulin sensitivity，muscle strength and hormone secretion in pre-diabetic state population

DOI：10.3969/j.issn.1006.7108.2018.11.011

中文关键词: 加压训练肌力激素分泌骨密度骨代谢骨质疏松

英文关键词:KAATSU training muscle strength hormone secretion bone mineral density bone metabolism osteoporosis

基金项目:

作者	单位
刘玉琳1* 叶琼2 刘昊为3	1. 重庆城市管理职业学院人文教育学院，重庆401331 2. 重庆幼儿师范髙等专科学校，重庆404047 3. 西南大学体育学院，重庆400715

摘要点击次数: 759

全文下载次数: 535

中文摘要:

目的探讨加压结合抗阻训练对糖耐量减低人群骨密度、胰岛素敏感性、肌力、激素代谢的影响，为推广改善胰岛素敏感性和骨健康的新运动处方提供参考。方法招募90名糖耐量减低人群，在实验前2周对所有受试者进行前测，前测内容包括腿部深蹲和腿举1RM测试、胰岛素敏感性、糖耐量测试、骨密度、骨代谢指标、腿部肌肉量、等速肌力测试、生长激素、血睾酮。所有受试者前测完成后进行随机分为对照组（C组）、加压搭配抗阻训练组（KR组）、抗阻训练组（R组），每组30人。分组完成后，按各组训练方案进行为期36周，每周5次的训练干预，36周训练干预结束后的3d内进行后测，后测项目与前测一致。利用SPSS统计软件对所有指标进行独立样本t检验和单因素方差分析。结果糖耐量试验后2 h血糖（oral glucose tolerance test 2 h，OGTT -2 h)、膜岛素抵抗指数(homeostasis model assessment insulin resistance, HOMA-IR)、尿羟脯氨酸 (hydroxyproline，HOP )、血浆抗酒石酸酸性鱗酸酶(tartrate resistant acid phosphatase，TRACP )、尿脱氧吡啶喏啉 (deoxypyridinoline，DPD)，KR组和R组的后测结果均显著低于前测和C组（P <0. 05)，KR组后测结果显著低于R组（P <0.05.。股骨颈骨密度、Ward三角骨密度、大转子骨密度，KR组和R组的后测结果均显著高于前测和C组（P<0. 05)。下肢肌肉量和下肢肌力，KR组和R组的后测结果均显著高于前测和C组（P<0. 05)，KR组后测结果显著高于R组（P <0. 05)。结论糖耐量减低人群进行加压结合抗阻训练能提高糖耐量，改善胰岛素敏感性，同时增加其骨密度，降低骨吸收作用，增加下肢肌力和肌肉量。加压造成的静脉池效应诱发的生长激素、IGF-1、睾酮的分泌量增加是造成上述现象的主要影响因素。

英文摘要:

Objective To investigate the effect of KAATSU (pressure) and resistance training on bone mineral density (BMD)， insulin sensitivity，muscle strength and hormone metabolism in pre-diabetic patients，and to provide references for the promotion of new exercise prescriptions for improving insulin sensitivity and bone health. Methods 90 pre-diabetic patients were enrolled into this study. All subjects had pre-test two weeks before the experiment. The pretest included 1RM test of leg squat and leg lift，insulin sensitivity, glucose tolerance test，bone mineral density，bone metabolic index, leg muscle mass，isokinetic muscle strength, jumping ability (vertical swinging and stepping swinging)，growth hormone (GH) and blood testosterone. All subjects were randomly divided into control group ( C group), KAATSU and resistance training group ( KR group) and resistance training group (R group)，with 30 subjects in each group. After the completion of the randomization，the training program for each group lasted for a period of 36 weeks，and participants had 5 times per week training intervention. At the end of the 36 weeks training intervention, post-test was conducted within 3 days, and the items were consistent with those of the pre-test. Using SPSS statistical software, independent samples t test and analysis of variance were performed. Results The post-test result of OGTT - 2 h, HOMA-IR, urinary HOP, urinary DPD and plasma TRACP in KR group and R group were significantly lower than those of pretest (P < 0. 05), and those in group C (P < 0. 05). The post-test result of these variables in group KR were significantly lower than those in group R (P < 0. 05). The post-test result of femoral neck BMD, Ward’s triangle BMD and greater trochanter BMD of KR group and R group were significantly higher than those of pre-test (P < 0. 05), and those of group C (P < 0. 05). The post-test result of lower extremity muscle mass and lower extremity muscle strength were significantly higher in the KR group and the R group than those of the pre-test (P < 0. 05) , and the post-test result of KR group were significantly higher than those of R group (P < 0. 05). Conclusion In pre-diabetic patients, KAATSU training combined with resistance training could reduce fasting blood glucose and fasting insulin, improve insulin sensitivity, and at the same time increase bone density, reduce bone resorption and increase muscle strength and muscle mass of lower limbs. The increase in growth hormone secretion, IGF - 1 and testosterone induced by venous pool caused by pressurization could be the main influencing factor of the above effects.

查看全文查看/发表评论下载PDF阅读器

关闭