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| 肌少症的CT、MR诊断及临床意义 |
| Clinical significance and diagnosis of sarcopenia with CT and MR |
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| DOI：10.3969/j.issn.1006.7108.2018.11.028 |
| 中文关键词: 肌少症 CT MR 临床意义 |
| 英文关键词:sarcopenia CT MR clinical significance |
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| 中文摘要: |
| 肌少症（sarcopenia）于1997年被正式定义，是一种与年龄相关、全身广泛性复杂综合征，主要特征为骨骼肌量减少、肌力下降和功能减退。肌少症发病率随年龄增大而逐渐增高，明显降低老年人的生活质量，提高老年人群死亡率，给家庭及社会带来了极大的负面影响。近年来肌少症受到国内外学者越来越多的关注。肌量的评估是诊断肌少症的重要方面。双能X线及生物电阻抗可测量全身肌量，但是精确程度不高。CT与MR目前被认为是评估骨骼肌量的形态学金标准。CT、MR骨骼肌形态学相关研究，与骨质疏松及脆性骨折的发生有密切关系，可以对老年人及各种疾病患者的预后及生存率进行预测，并对身体成分及增肌训练的效果进行监测。临床在进行CT及MR检查，尤其是对老年人进行检查的同时应注意对肌少症的筛查与诊断。本文就肌少症的CT、MR诊断及其临床意义做一综述。 |
| 英文摘要: |
| Sarcopenia is first proposed in 1997. It is a age-related, systematic, and complicated syndrome, characterized by reduction of skeletal muscle volume and decrease of skeletal muscle strength and function. The incidence rate sarcopenia gradually increases with increasing age. It seriously affects the quality of life of the elderly, increases mortality, and brings a significant burden to the family and community. Sarcopenia has attracted more and more attention from domestic and foreign scholars in recent years. The assessment of muscle mass is an important aspect for diagnosis of sarcopenia. The whole body mass can be measured using dual energy X-ray (DXA) and bioelectrical impedance analysis (BIA), but the accuracy is low. CT and MR are currently considered as morphological gold standards for assessing skeletal muscle mass. Studies with CT and MR show that skeletal muscle morphology is closely related to osteoporosis and the occurrence of brittle fracture. It can predict the prognosis and survival of the elderly and patients with various diseases, and monitor body composition and the effect of muscle training. It should be paid more attention to the screening and diagnosis of sarcopenia in clinical CT and MR examination, especially for the elderly. This article reviews the diagnosis of sarcopenia with CT and MR and its clinical significance. |
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