| According to the standard methods and procedures for the development of evidence-based medicine guidelines, a multi-disciplinary guideline development working group was established. Through the process of guideline registration, guideline plan writing, analysis of relevant guidelines, clinical problem screening and determination, clinical evidence retrieval and evaluation, forming of recommendation, etc. and after three rounds of discussions by the consensus expert group, a new evidence-based guideline for diagnosis and treatment of senile osteoporosis in China (2018) was developed. The grading of recommendations assessment, development and evaluation (GRADE) system was used to rate the quality of evidence and the strength of recommendations. Recommendations were derived from body of evidence, and at the same time considered the balance of benefits and harms as well as values and preferences of Chinese patients. The guideline development working group developed 15 recommendations for the diagnosis and treatment of senile osteoporosis. The guideline covered the screening for senile osteoporosis, risk assessment, diagnosis, basic treatment, multiple anti-osteoporosis drugs, therapeutic effect monitoring and evaluation of senile osteoporosis. This guideline aims to provide scientific evidence for clinicians and patients in China. |