中国苏州地区老年女性中骨质疏松症危险因素的筛选
Screening of the risk factors for osteoporosis in elderly women in Suzhou China
  
DOI:10.3969/j.issn.1006-7108.2018.12.016
中文关键词:  亚洲人骨质疏松自我筛查工具  骨质疏松症  危险因素  有序Logistic回归
英文关键词:OSTA  osteoporosis  risk factors  ordinal logistic regression
基金项目:国家自然科学基金(81473046,31271336,81373010,81502868,81571291,81573253,31401079)
作者单位
马冬亮 高红琴 朱侃 谷红波 雷署丰* 1.苏州大学医学部公共卫生学院遗传流行病与基因组学研究中心江苏 苏州 215213 2.江苏省老年病预防与转化医学重点实验室江苏 苏州 215213 3.江苏苏州高新区狮山街道社区卫生服务中心江苏 苏州 215009 4.江苏苏州姑苏区平江街道娄江社区卫生服务中心江苏 苏州 215001 
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中文摘要:
      目的 筛选与评估骨质疏松症的相关危险因素,为骨质疏松症的防治提供依据。 方法 选择3 915名苏州地区绝经后妇女,基于亚洲人骨质疏松自我筛查工具(osteoporosis self-assessment tool for asians,OSTA)指数将人群分为骨质疏松(osteoporosis, OP)低风险组(>-1)、中风险组(-1~-4)和高风险组(<-4),对其饮食习惯及女性健康史进行问卷调查。结果 怀孕次数、累计母乳喂养时间、绝经年龄、月经持续年限、茶、经常吃的肉的种类、最近一周吃油炸食品的数量、绝经类型、是否子宫切除组间差异有统计学意义(P<0.05),上述变量是OP相关的危险因素。由有序Logistic回归分析结果显示,怀孕次数、绝经年龄、经常喝茶、绝经类型等与OP风险显著相关(P<0.05),而且怀孕次数与哺乳时间存在交互作用。结论 苏州地区老年绝经女性的月经史、怀孕史、饮食习惯等都是骨质疏松的重要风险因素。
英文摘要:
      Objective The aim of this study was to evaluate the risk factors of osteoporosis (OP) and to provide theoretical basis for the prevention and treatment of osteoporosis. Methods 3 915 postmenopausal women in Suzhou were classified into three groups of osteoporosis risk (low-risk, mid-risk and high-risk) according to OSTA (osteoporosis self-assessment tool for asians) and their dietary habits and female history were investigated by questionnaire survey. Results Factors including number of pregnancy, accumulative time for breastfeeding, menopausal age, menstruation history, tea, the species of favorite meat, the quantity of fried food intake in the previous week, menopausal type and hysterectomy were significantly different among the three groups (P<0.05). Further ordinal logistic regression analyses showed that several factors, such as number of pregnancy, menopausal age, tea and menopausal type were significantly associated with the risk of OP (P<0.05). There was an interaction effect between the number of pregnancy and the accumulative time for breastfeeding. Conclusion Menstruation history, pregnancy history and dietary habits were important risk factors of osteoporosis in postmenopausal women in Suzhou city.
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