肠道菌群对骨代谢影响的研究进展
Research progress on the effect of gut microbiota on bone metabolism
  
DOI:10.3969/j.issn.1006-7108.2018.12.017
中文关键词:  肠道菌群  骨代谢  骨质疏松
英文关键词:gut microbiota  bone metabolism  osteoporosis
基金项目:国家自然科学基金面上项目(81570489);卫计委国家临床重点专科建设项目资金
作者单位
陈晨 王邦茂* 冯淑芝 王琳 1.天津医科大学总医院保健医疗部,天津 300052 2.天津医科大学总医院消化科天津 300052 
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中文摘要:
      肠道菌群在人体中发挥着重要的作用,与人体的骨量减低及骨质疏松的发病相关。其可能通过自身代谢产物,影响宿主代谢及免疫系统等几方面来影响破骨细胞和成骨细胞的相对活性,从而影响骨代谢,甚至导致骨质疏松。本文将从上述几个方面对肠道菌群对骨代谢的影响进行综述。
英文摘要:
      Gut microbiota plays an important role in the human body, and is associated with reduced bone mass and osteoporosis. It may affect the relative activity of osteoclasts and osteoblasts, even bone metabolism, and leads to osteoporosis by its metabolic product, influences on metabolism of the host and immune system, and so on. This article reviewed the research progress on the effect of gut microbiota on bone metabolism from the above aspects.
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