Osteoporosis is a kind of systemic bone disease, highly prevalent in the elderly, and is the main cause of disability and death in elderly patients. The occurrence and development of osteoporosis is not only related to the decrease of bone mass and the increase of fat content in the bone marrow, but also closely related to the volume and strength of skeletal muscle. In view of the important role of cytokines in bone, muscle and adipose tissue in this process, we focused the following review on cytokines that receive great attention recently, including bone morphogenetic protein, transformation growth factor beta, fibroblast growth factor, etc. in order to provide a new perspective for the early diagnosis, curative effect observation and complication treatment of osteoporosis. |