肠道菌群与骨质疏松症中西医研究进展
The research progress on osteoporosis and intestinal microflora in traditional Chinese medicine and western medicine
  
DOI:10.3969/j.issn.1006-7108.2018.12.025
中文关键词:  骨质疏松症  肠道菌群  骨量  破骨细胞  中医药
英文关键词:osteoporosis  intestinal microflora  bone mass  osteoclast  traditional Chinese medicine
基金项目:国家自然科学基金(81603574,81573944,81774286);安徽省自然科学基金(1708085QH213);国家中医临床研究基地业务建设第二批科研专项(JDZX2015123);国家中医药管理局中医药重点学科中医内分泌学(20091221)
作者单位
赵进东 余婵娟 张文锦 刘蒙蒙 张璐 尤良震 刘剑 舒仪琼 方朝晖* 1. 安徽中医药大学第一附属医院内分泌科,安徽 合肥 230031 2. 安徽省中医药科学院中医药糖尿病防治研究所安徽 合肥 230012 3. 新安医学教育部重点实验室安徽 合肥 230038 
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中文摘要:
      骨质疏松症在我国广泛流行,严重影响老年人的生存质量,并给患者、家庭、社会造成严重的心理负担和经济负担。近年来肠道微生态的研究已成为热点,其对骨质疏松症的影响也被人们所关注。本文从肠道菌群与骨质疏松症的紧密关系、基于肠道菌群治疗骨质疏松症的临床研究与实验研究等方面进行综述,总结中西医在该方向的研究进展,为骨质疏松症的临床治疗提供一种新方法。
英文摘要:
      Osteoporosis is widely prevalent in our country. It has a serious impact on the life quality of the elderly, and serious economic burdens and psychological burdens on patients, families and society. In recent years, the research of intestinal microflora has aroused great concern, and more and more attention has been paid to the effect of its therapeutical function on osteoporosis. This review summarizes the progress and hotspots in recent Traditional Chinese Medicine and Western Medicine researches of the close associations among intestinal microflora and osteoporosis, the clinical and experiment study on the treatment of osteoporosis through modulate intestinal microflora. This may provide a new methods for the clinical treatment of osteoporosis.
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