| Objective To investigate the relationship among bone mineral density (BMD), TCM syndromes, and the influential factors in middle-aged and elderly women with osteoporosis in Guangdong province. Methods A total of 1453 osteoporosis patients were inquired with age, menopause age, menopausal period, history of fracture, BMD of hip and lumbar vertebrae, et al. The data were analyzed using software SPSS 20.0 editions. Results A total of 373 samples were obtained, aging from 48 to 95 years old, with the average of 73.56±9.32 years old. Among those, 130 cases were with spleen and kidney yang deficiency syndrome (34.85%), 161 cases with Yin deficiency of liver and kidney syndrome (43.16%), 75 cases with Qi stagnation and blood stasis syndrome (20.11%), and 7 cases with other syndromes (1.88%). BMD was significantly different among difference age groups, menopause age groups, and menopausal period groups (P<0.05). BMD was significantly different between the patients having and having not the history of fracture, and between having and having not parental fractures (P<0.05). BMD of patient with spleen and kidney Yang deficiency syndrome was higher than that of patients with Yin deficiency of liver and kidney syndrome (P<0.05). The patients who had been treated for more than 6 months were better than those treated less than 6 months in terms of improvement of joint movement. The efficacy was better in patients with Yin deficiency of liver and kidney syndrome or spleen and kidney Yang deficiency syndrome who received treatment for more than half a year. Conclusion There is a certain difference in BMD among middle-aged and elderly women with osteoporosis in Guangdong. Age, menopause age, menopausal period, and patients with fracture history or parent history of fracture are influential factors of BMD. The efficacy is various in patients with different TCM syndrome or with different treatment time. |