| Objective To explore the clinical effect of triple therapy for postmenopausal women with osteoarthritis and osteoporosis. Methods From April 2017 to March 2018, 64 cases of postmenopausal osteoarthritis with osteoporosis were studied in our hospital. According to the simple randomization method, the patients were divided into the control group and the observation group. The control group was treated with non-steroid drugs (NSAID) and sodium hyaluronate, and the observation group was treated with NSAID, sodium hyaluronate and calcitonin. The therapeutic effects of the two groups were compared, and the changes in VAS score, Lysholm knee score, WOMAC score and waist bone mineral density before and after treatment were compared. Results The effective rate of the control group was 78.13%, the effective rate of the observation group was 93.75%, and the effective rate of the observation group was higher than that of the control group (P<0.05). Bone mineral density of the two groups after treatment was higher than that before treatment (P<0.05), and bone mineral density of the observation group was higher than that of the control group at 3 months and 6 months after treatment (P<0.05). After treatment, the VAS score, Lysholm knee score and WOMAC score of the two groups were lower than those before treatment (P<0.05), and at 3 months and 6 months after treatment, the VAS score, the Lysholm knee score and the WOMAC score in the observation group were all lower than those of the control group (P<0.05). Conclusion The combination of NSAID, sodium hyaluronate and calcitonin in the treatment of postmenopausal women with arthritis and osteoporosis could not only improve the therapeutic effect, improve the function of the knee joint, but also improve the activity and the quality of life of the patients. It could play a positive role in the clinical application. |