3 326例南京地区人群维生素D水平与季节关系调查
Study on the relationship between vitamin D level and season in 3326 Nanjing residents
  
DOI:10.3969/j.issn.1006-7108.2019.02.025
中文关键词:  维生素D缺乏  25羟维生素D  季节
英文关键词:vitamin D deficiency  25-hydroxyvitamin D  season
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作者单位
包金晶 戴芳芳* 南京中医药大学附属医院内分泌科江苏 南京 210000 
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中文摘要:
      目的 通过测定江苏省中医院2017年就诊患者体内25羟维生素D[25(OH)D]水平,分析目前维生素D水平状况并评价其与季节的关系。方法 收集2017年1月1日至2017年12月31日在江苏省中医院测25(OH)D水平的门诊及住院患者3 326例,主要来源于内分泌科、生殖医学科、体检中心等就诊的南京市居民,排除相关影响因素,分别比较不同季节、性别的25(OH)D水平和维生素D营养状况差异。结果 3 326例患者的25(OH)D的平均水平为18.38 ng/mL,维生素D缺乏率为63.3%,不足率为29.0%,正常率为7.7%;春夏两季维生素D水平高于秋冬两季(P<0.05);女性维生素D水平明显低于男性(P<0.05)。结论 南京地区人群存在不同程度的维生素D缺乏,且具有季节差异性,秋冬季节25(OH)D的水平更低,与性别也相关联。维生素D作为人体内不可缺少的维生素对骨骼系统具有重要作用,提高公众合理补充维生素D的意识并针对高危人群及时补充钙剂是必要的,定期检测25(OH)D作为评估体内维生素D水平的常规实验室检查,为临床正确应用维生素D提供科学的理论依据。
英文摘要:
      Objective To evaluate vitamin D status and study its relationship with seasons by measuring the levels of 25-hydroxyvitamin D [25(OH)D] in patients admitted to Jiangsu Province Hospital of TCM in 2017. Methods We recruited 3326 cases of outpatients and inpatients who had 25(OH)D measured from January 01, 2017 to December 31, 2017 in Jiangsu Provincial Hospital of TCM, mainly residents of Nanjing City, including department of endocrinology, department of reproductive medicine and physical examination center, excluding related influencing factors, comparisons were made on the differences in 25(OH)D levels and vitamin D nutritional status between different seasons and sexes. Results The average level of 25(OH)D in the 3326 patients in Jiangsu Province Hospital of TCM was 18.38 ng/ml, the vitamin D deficiency rate was 63.3%, the insufficiency rate was 29.0%, and the normal rate was 7.7%. Vitamin D levels in the Spring and Summer group were higher than those in the Autumn and Winter group (P?0.05). Vitamin D levels in women were significantly lower than those in men (P?0.05). Conclusion Residents in Nanjing have different degrees of vitamin D deficiency, and lower levels of 25(OH)D in autumn and winter. It is also associated with gender. Vitamin D is an indispensable vitamin in the human body and plays an important role in the skeletal system. It is necessary to increase the public’s awareness of the rational use of vitamin D supplementation and provide timely calcium supplements to high-risk groups. Regular testing of 25(OH)D as a routine laboratory test to assess vitamin D levels in the body is a way to provide scientific theoretical basis for the correct application of vitamin D in clinical practice.
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