中药复方治疗绝经后骨质疏松症的临床研究概况
Clinical research of Chinese herbal compound treatment of postmenopausal osteoporosis
  
DOI:10.3969/j.issn.1006-7108.2019.02.029
中文关键词:  绝经后骨质疏松  中药复方  临床研究
英文关键词:postmenopausal osteoporosis  Chinese herbal compound  clinical research
基金项目:国家中医药管理局中医临床研究基地业务建设科研专项(JDZX2015080);甘肃省省属科研院所基础条件建设专项(1505TTCA020);兰州市人才创新创业项目(2015-RC-23);兰州市科技计划项目(2016-3-102)
作者单位
黄晋1,2 李建国3* 谢兴文1,2 李晶1,2 李宁3 许伟1,2 潘鑫戊2 1.甘肃省中医药研究院甘肃 兰州 730050 2.甘肃省中医院甘肃 兰州 730050 3.甘肃中医药大学甘肃 兰州730000 
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中文摘要:
      绝经后骨质疏松症为骨吸收大于骨形成的高转化型代谢性骨病,其并发症严重影响患者的生活水平及质量。中医认为本病与肝、脾、肾脏腑亏虚及血瘀等关系密切。近年来临床研究发现,中药复方治疗绝经后骨质疏松症效果明显,能够有效地改善患者的骨代谢水平,增加患者的骨密度,同时改善患者的临床症状。笔者就中药复方治疗绝经后骨质疏松的作用机制及临床疗效进行综述,旨在为中药复方治疗绝经后骨质疏松症提供数据支持及指导,为今后中药复方开发及靶向治疗绝经后骨质疏松症提供思路。以期指导临床辩证用方,提高对绝经后骨质疏松症的防治率。
英文摘要:
      Postmenopausal osteoporosis is a metabolic bone disease with greater bone resorption than bone formation, and its complications seriously affect the quality of life and everyday living of patients. Chinese medicine believes that this disease is closely related to liver, spleen and kidney deficiency and blood stasis. In recent years, clinical studies have found that traditional Chinese medicine has evident effects on the treatment of postmenopausal osteoporosis, and can effectively improve the level of bone metabolism, increase bone density, and at the same time improve the clinical symptoms of patients. This article summarizes the mechanism of action and clinical curative effect of traditional Chinese medicine compound on the treatment postmenopausal osteoporosis. The aim is to provide data to support and guide the use of Chinese herbal compound for the treatment of postmenopausal osteoporosis, and to provide ideas for the development of traditional Chinese medicine compound and the targeted treatment of postmenopausal osteoporosis. It is expected to guide clinical dialectical prescriptions and improve the prevention and treatment of postmenopausal osteoporosis.
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