绝经后妇女的生殖特征和骨密度相关性研究
Study on the correlation between reproductive characteristics and bone mineral density in postmenopausal women
  
DOI:10.3969/j.issn.1006.7108.2019.03.006
中文关键词:  骨密度  骨质疏松症  生殖因素  绝经后女性
英文关键词:bone mineral density  osteoporosis  reproductive factors  quantitative ultrasound  postmenopausal women
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作者单位
姜剑魁1 宋晓燕2* 1.山东省东营市胜利油田中心医院手足外科山东 东营257000 2.山东省东营市胜利油田中心医院妇产超声科山东 东营257000 
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中文摘要:
      目的 探讨绝经后妇女生殖特征与骨密度之间的关系。方法 2014年3月至2016年7月入住本院收治的200例绝经后骨质疏松症女性被选为候选人。记录了一些社会人口、生活方式和生殖因素。使用双能X射线吸收测量法测量腰椎1-4(L1-4)的BMD。Pearson相关检验和多元回归分析评估生殖因素与骨密度的相关性。结果 绝经年龄与骨密度无显著相关性,绝经年数、月经初潮年龄、妊娠次数和总泌乳期与其成负相关。在生殖因素中,调整年龄、体质指数、活动和钙摄入量后,泌乳持续时间和骨密度之间的呈现显著负相关性。结论 除延长泌乳总时间外,其他生殖因素与绝经后妇女骨密度无显著相关性。
英文摘要:
      Objective To examine the relationship between reproductive characteristics and bone mineral density (BMD) in postmenopausal women. Methods A total of 200 menopausal women with osteoporosis admitted to our hospital from March 2014 to July 2016 were selected as candidates. Some socio-demographic, life style, and reproductive factors were recorded. BMD of the lumbar spine 1-4 (L1-4) was measured using dual energy X-ray absorptiometry. Correlations between reproductive factors and BMD were assessed by Pearson's correlation test and multiple regression analysis. Results Age at menopause was not significantly correlated with BMD. The years after menopause, age at the first menstrual period, number of pregnancies, and total lactation periods were negatively correlated with BMD. Among reproductive factors, only the association between lactation duration and BMD remained significant after adjusting for age, body mass index, activity, and calcium intake. Conclusion The results indicate that except for prolonged total time of lactation, other reproductive factors are not significantly associated with BMD in postmenopausal women.
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