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| 老年高血压女性患者心率与骨密度相关性研究 |
| Relationship between heart rate and bone mineral density in elderly women with hypertension |
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| DOI：10.3969/j.issn.1006.7108.2019.03.013 |
| 中文关键词: 心率 骨质疏松症 老化 女性 高血压 |
| 英文关键词:heart rate osteoporosis aging women hypertension |
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| 中文摘要: |
| 目的 探讨高血压患者心率与骨密度(bone mineral density, BMD)的相关性。方法 选取2014年4月至2018年1月期间在我院就诊的老年高血压患者490例。收集患者BMD等临床及实验室数据。根据世界卫生组织标准，骨质疏松症被定义为T评分为–2.5或更低。结果 即使在调整年龄、白细胞计数、空腹血糖和甘油三酯水平后，心率高的受试者BMD明显较低。这些受试者的骨质疏松患病率也明显偏高。在多因素Logistic回归分析中，高心率组的患病率为低心率组1.67倍，骨质疏松症患者的心率较低，与年龄、体质量指数、合并症和实验室指标无关。结论 在老年高血压女性中，高心率与低BMD独立相关；当治疗患有高血压和高心率疾病的老年女性时，主动监测BMD可能会有所帮助。 |
| 英文摘要: |
| Objective To determine whether high heart rate is associated with low bone mineral density (BMD) in elder women with hypertension. Methods Four hundred and nighty elderly hypertensive patients attending to our hospital from April 2014 to January 2018 were selected. BMD profiles and clinical and laboratory data were collected. Osteoporosis was defined as a T-score of –2.5 or less according to World Health Organization criteria. Results BMD was significantly lower in participants with a high heart rate, even after adjustment for age, diabetes mellitus, white blood cell count, and fasting glucose and triglyceride levels. The prevalence of osteoporosis was also significantly higher in those participants. In multivariate logistic regression analysis, the group with high heart rate was 1.67 times as likely (95% confidence interval 1.2–2.3) to have osteoporosis comparing to the group with lower heart rate, independent of age, body mass index, comorbidities, and laboratory findings. Conclusion High heart rate is independently associated with lower BMD in older women with hypertension. Proactive surveillance of BMD could be helpful when managing elder women with hypertension and a high heart rate. |
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