骨移植替代材料在骨质疏松性骨折中的应用
Application of bone graft substitute in the management of osteoporotic fractures
  
DOI:10.3969/j.issn.1006-7108.2019.04.024
中文关键词:  骨质疏松性骨折  骨移植替代材料  骨质疏松症
英文关键词:osteoporotic fracture  bone graft substitute  osteoporosis
基金项目:国家自然科学基金(81401793,81572132); 江苏省“六大人才高峰”高层次人才项目(2016-wsw-060); 南京市医学科技发展资金(QRX17007)
作者单位
旦增欧珠 施鸿飞* 林华 南京大学医学院附属鼓楼医院江苏 南京 210008 
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中文摘要:
      骨质疏松性骨折由于骨量降低和骨微细结构被破坏,手术后易发生内固定松动和失败。骨移植替代材料是一类在骨科手术中用于代替骨移植的天然或合成材料。目前临床上常用的骨移植替代材料包括钙磷陶瓷材料、聚合材料等,其在骨质疏松性骨折手术治疗时可用于填充骨缺损、增加骨强度、促进骨折愈合,从而降低复位丢失和内固定的失败率,具有良好临床效果。
英文摘要:
      Due to reduced bone mass and deteriorated micro-structure, osteoporotic fracture is prone to postoperative complications including implant loosening or failure. Bone graft substitutes are used to fill bone defects, promote bone healing, and increase bone strength. At present, the commonly used bone graft substitutes include calcium phosphate ceramic materials, polymeric materials and so on. They have been applied in the treatment of osteoporotic fractures and achieved good results.
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