中国骨质疏松杂志

原发性骨质疏松症的中医药防治研究进展

Research progress on the prevention and treatment of primary osteoporosis by Chinese medicine

DOI：10.3969/j.issn.1006-7108.2019.04.026

英文关键词:primary osteoporosis Chinese medicine acupuncture, other therapies review

基金项目:国家自然科学基金（81173621、81473703、81073114、81674003、81774342）; “中医骨伤科学”国家重点学科（100508）; 海派中医流派传承研究基地（ZY3-CCCX-1-1003）;“上海市重中之重重点学科（中医骨伤科学）”重中之重临床医学中心和重点学科建设项目（2017ZZ02024）

作者	单位
张云飞1 安军伟1 龚幼波1 陈东煜2*	1. 上海中医药大学，　上海　201203 2.上海中医药大学附属曙光医院石氏伤科医学中心，上海 201203

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中文摘要:

原发性骨质疏松症(primary osteoporosis，POP)是老年人以及绝经后女性的常见病、多发病。据调查显示,我国拥有60岁以上人口1.4亿，而50岁以上女性人群骨质疏松症发病率为20.7%,男性为14.4%,并呈逐年上升趋势。POP导致的骨折也是老年人致残、致死的主要原因之一。因此，POP的预防及治疗已成为当今人类重要的公共健康问题。近年来许多研究者从分子生物学水平研究中医药治疗原发性骨质疏松症并取得了明显的进展，越来越多的基础及临床研究证实中医药在治疗该病方面有着独特的优势。本文主要就近3年的相关文献进行总结，从中药、针灸、其他疗法等方面将近年来中医药防治该病的研究进展作一综述，旨在方便各位学者及时获得相关研究进展信息，并指出现有研究中存在的不足，以期能进一步探索有效而安全的治疗方案，更好的指导科研和临床工作。

英文摘要:

Primary osteoporosis (primary osteoporosis, POP) is a common and frequently occurring disease in the elderly and postmenopausal women. According to investigation and research, China has a population of 140 million aged 60 years and over, and in those aged 50 years and over the incidence of osteoporosis is 20.7% in females and 14.4% in males, with a trend of increase each year. POP-induced fractures are also one of the leading causes of disability and death in the elderly. Therefore, the prevention and treatment of POP has become an important public health problem in today's society. In recent years, many researchers have made significant progress in the treatment of primary osteoporosis from the level of molecular biology, and more and more basic and clinical studies have confirmed that traditional Chinese medicine has its unique advantages in the treatment of this disease. This paper summarizes the relevant literatures of the recent three years, from the aspects of Traditional Chinese medicine, acupuncture and other therapies. This paper makes a comprehensive exposition on the research progress of TCM in the prevention and treatment of osteoporosis in recent years, aiming at facilitating the scholars to obtain relevant research progress information in a timely manner, and pointing out the deficiencies in the existing research, so as to further explore effective and safe treatment plan, and to better guide the research and clinical work.

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