| Objective To investigate the correlation between lower limb microcirculation disease and osteoporosis in elderly male patients with type 2 diabetes. Methods A total of 120 patients hospitalized in the Department of Geriatrics in our hospital were enrolled in the study. The patients were divided into three groups according to the foot back baseline value TcpO2: normal group (A)TcpO2 > 40 mmHg, mild abnormal group (B) 20 mmHg < TcpO2 < 40 mmHg, and severe abnormal group (C)TcpO2 < 20 mmHg. There were 42 cases in group A, 42 cases in group B, and 36 cases in group C. The age, duration of disease, body mass index (BMI), blood calcium (Ca), glycated hemoglobin (HbA1c), and low density lipoprotein cholesterol (LDL-C) were measured. The baseline TcpO2 of the foot was measured with noninvasive percutaneous oxygen pressure in our hospital. bone mineral density (BMD) of L1-5, the hip, the femoral neck, and the intertrochanter was measured with dual energy X-ray absorptiometer. Results BMD of L5 and the total hip in the mild abnormal group and the severe abnormal group was lower than that in the normal group, and the difference was statistically significant (P<0.05). Pearson correlation analysis showed that the TcpO2 value of the elderly male T2DM patients was positively correlated with BMD of L4, L5, and the total hip (r=0.254, 0.343, 0.202, P<0.05), and the difference was statistically significant. Conclusion There is a certain correlation between osteoporosis and the lower limbs microcirculation disease, which is a risk factor for the occurrence of osteoporosis. Early detection of the diabetic lower limp microcirculation disease may help to prevent osteoporosis.
Key words: osteoporosis; elderly men; type 2 diabetes; lower limb microcirculation disease |