Objective To study 3881 middle-aged and elderly patients in our hospital by using fracture risk assessment tool (FRAX) ,and to explore and analyze the relationship between the risk of major fracture (PMOF) and hip fracture probability (PHF) in the next 10 years and FRAX in condition of having been detecting femoral neck bone mineral density (BMD). Methods From Jan. to Dec. 2017, 3881 cases in the First Hospital of Putian were retrospectively analyzed, in whom 1218 were males, 2663were females,they all were detected femoral neck BMD by dual-energy X-ray absorptiometry (DXA) .According to the ages, they were devided into five groups, 40-49, 50-59, 60-69,70-79 years old and over 80 year old respectively. The data were analysed using the model of "China" FRAX software.Results Among the 3881 participants, there were 1954 cases (51%) were included in the abnormal BMD group and 1927 cases (49%) in the normal BMD group.Compared with the normal BMD group, the abnormal BMD group had higher age, lower weight, more height loss and lower body mass index (BMI) (P < 0.001). In the conditions with or without a BMD when usingthe FRAX tool, the PMOF and PHF (%) in the abnormal BMD group were significantly higher than those in the normal group (P < 0.001)with FRAX.The relationship between PMOF predicted by FRAX and femoral neck bone mineral density was significantly negative correlation.In different age groups, 40-49, 50-59, 60-69,and 70-79 and over 80 year old groups, abnormal BMD rates were 28.9%, 40.1%, 53.9%, 68.2%, and 76.2%, with an average of 50.3%, along with the increase of age, a significant rise in PMOF, and differences between groups with a statistical significance (P < 0.001).With or without BMD values, PMOF and PHF (%) in the abnormal BMD group were significantly higher than that of in the normal BMD group (P < 0.001).Conclusion With or without inputting femoral neck BMD value and the application of FRAX, all participants in the next 10 years the main fracture risk probability increases along with the age increased.It is recommended that the FRAX as a basic osteoporosis screening tool can be popularized in our country by the lack of DXA. The probability of osteoporosis fracture in our country is lower than those in abroad, this needs further research. |