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| 肌肉强度和肌肉质量与绝经后女性骨密度的相关性研究 |
| Relationship between muscle strength, muscle mass and bone mineral density in postmenopausal women |
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| DOI：10.3969/j.issn.1006.7108.2019.07.012 |
| 中文关键词: 肌肉强度 肌肉质量 肌肉骨骼系统 骨密度 绝经后女性 |
| 英文关键词:muscle strength muscle mass musculoskeletal system bone mineral density postmenopausal women |
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| 中文摘要: |
| 目的 探索绝经后女性肌肉强度和肌肉质量与骨密度相关性。方法 分析了2014年3月至2017年8月在我院就诊的340名绝经后妇女。使用双能量X射线吸收测定法检测股骨颈和腰椎骨密度(bone mineral density，BMD)、全身骨密度和附肢骨骼肌肌肉量(appendicular skeletal muscle，ASM)。ASM指数(ASMI，kg/m2)按照ASM(kg)除以高度的平方(m2)计算。测量握力(kg)作为肌肉力量的指标。结果 调整ASMI和年龄后(股骨颈标准化偏回归系数β=0.105，腰椎=0.116)，握力强度与几个骨骼部位BMD呈显著性正相关(P＜0.05)。股骨颈和腰椎骨密度的调整平均值显示出握力强度从最低到最高三分位数的显著增加趋势。本研究结果表明肌肉强度与绝经后妇女肌肉量的几个位点的BMD密切相关。无论肌肉大小如何，肌力强健的绝经后妇女都有健康的骨骼状态。结论 绝经后女性骨密度和肌肉强度密切相关，与肌肉质量无明显相关性。 |
| 英文摘要: |
| Objective To explore the correlation between muscle strength, muscle mass and bone mineral density in postmenopausal women. Methods This study analyzed 340 postmenopausal women who attended our hospital between March 2014 and August 2017. Areal bone mineral density (BMD) at the femoral neck and lumbar spine, whole-body bone mineral density, and appendicular skeletal muscle mass (ASM, kg) were measured by dual-energy X-ray absorptiometry. The ASM index (ASMI, kg/m2) was calculated as ASM divided by height squared (m2). Grip strength (kg) was measured as an indicator of muscle strength. Results Grip strength showed significant (P<0.05) positive relationships with BMD at several skeletal sites after adjusting for ASMI and age (standardized partial regression coefficient (β)=0.105 at femoral neck, β=0.116 at lumbar spine). Adjusted means of BMD at the femoral neck and lumbar spine showed significant increasing trends from the lowest to highest tertile of grip strength. Our findings indicate that muscle strength is associated with BMD at several sites independently of muscle mass in postmenopausal women. Postmenopausal women with strong muscle strength tend to have healthy bone status regardless of muscle size. Conclusion Bone mineral density is closely related to muscle strength in postmenopausal women, and there is no significant correlation with muscle mass. |
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