| Objective To summarize and analyze the bone mineral density (BMD) of the lumbar vertebrae 1-4, the femoral neck, and the hip joint, and other clinical features of peri-menopausal women. Methods A total of 183 perimenopausal women who underwent bone mineral density examination with dual-energy X-ray absorptiometry in our hospital from December 2017 to June 2018 were collected. BMD of the L1-L4 vertebral body area, the left femoral neck, and the left hip was measured. The relationship among age, body mass index (BMI), and osteoporosis was analyzed. Results Of the 183 patients, 39 (21.3%) were found to have osteoporosis. Among them, 33 cases (18.0%), 20 cases (10.9%), and 13 cases (7.1%) of osteoporosis were found in the lumbar 1-4, the left femoral neck, and the left hip, respectively. The bone status consistency between the total lumbar vertebrae and the femoral neck, the total lumbar vertebrae and the hip bones were 70.5% (129 cases) and 65% (119 cases), respectively. The consistency between the femoral neck and the hip was 74.9% (137 cases). BMD from high to low in the osteoporosis group, the osteopenia group, and the normal bone mass group was at the lumbar vertebrae 1-4, the left hip, and the left femoral neck, and the differences between the groups were statistically significant. Age and BMI were associated with the occurrence of osteoporosis. Osteoporosis was positively correlated with age, but negatively correlated with BMI, BMD of the lumbar vertebrae 1-4, left femoral neck, and left hip. BMD of the lumbar vertebrae 1-4 was most associated with osteoporosis. Conclusion The overall BMD of the lumbar spine shows a false increase trend. The sensitivity and specificity of BMD in the diagnosis of osteoporosis are 84.6% and 100% at the lumbar 1-4, 51.3% and 100% at the femoral neck, and 33.3% and 100% at the hip, respectively. The increase in age and decrease in BMI may increase the risk of osteoporosis in perimenopausal women. |