青年女性腰椎骨密度与体脂分布的相关性
Correlation between lumbar spine bone mineral density and body fat distribution in young women
  
DOI:10.3969/j.issn.1006.7108.2019.09.016
中文关键词:  青年女性  瘦身  骨质疏松  骨密度  定量CT
英文关键词:young women  slimming  osteoporosis  body mass index  quantitative CT
基金项目:陕西省自然科学基金面上项目(2017JM8152)
作者单位
刘正华 张玉婷 常荣 朱名 姜永宏* 西安交通大学附属红会医院影像科 陕西 西安 710061 
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中文摘要:
      目的 研究女性骨密度峰值阶段腰椎骨密度与体脂分布的相关性,探讨青年女性瘦身与老年骨质疏松症发生的关系。方法 纳入一组25~35岁的女性志愿者,采集每位志愿者的一般信息(身高、体重、腰围、臀围),计算体质量指数(body mass index,BMI)和腰臀比 (waist-hip ratio,WHR)。依据BMI将其分为两组,瘦型(BMI<21.4)和胖型(BMI≥21.4)。利用Midways pro定量CT(QCT)分析系统,测量脐水平腹内脂肪面积(visceral fat area,VFA)、腹壁脂肪面积(subcutaneous fat area,SFA)、腰椎2~4的骨密度(bone mineral density,BMD),计算腹脂比(VF/SF)及腰椎平均BMD(vBMD)。两组间体脂参数、vBMD的差异比较采用独立样本t检验,vBMD与体脂参数的相关性采用Pearson相关性检验。结果 纳入共计95名志愿者,其中瘦型43名,胖型52名。两组间VFA、SFA比较差异具有统计学意义,P值分别为0.01、0.003;两组间腰臀比、VF/SF、vBMD比较差异没有统计学意义;青年女性腰椎vBMD与VF/SF呈显著性相关(r=0.381,P=0.034)。 结论 女性腰椎峰值骨密度与BMI、腰围、臀围、VFA、SFA不具有相关性,与腹脂比(VF/SF)显著相关。青年女性科学瘦身不会降低机体骨密度储备。
英文摘要:
      Objective To investigate the relationship between the slimming of young women and the occurrence of senile osteoporosis, by studying the correlation between peak bone mass (PBM) of lumbar vertebrae and body fat distribution in young women. Methods A group of 25-35 year-old female volunteers were divided into two groups according to body mass index (BMI): lean type (BMI < 21.4) and fat type (BMI ≥ 21.4). General information including height, weight, waist circumference (WC) and hip circumference (HC) of each volunteer was collected to calculate BMI and waist-hip ratio (WHR). The abdominal visceral fat area (VFA) and subcutaneous fat area (SFA) at the umbilicus level, and the BMD of lumbar vertebrae 2-4 were measured by Mindways quantitative CT (QCT) Pro analysis system. The ratio of VF/SF, and the average lumbar BMD (vBMD) were calculated. The differences in WHR, VFA, SFA, VF/SF and lumbar spine BMD between groups were compared using independent sample t test, and the correlation between vBMD and anthropometric parameters was analyzed using Pearson correlation test. Results A total of 95 volunteers were included, of which 43 were thin and 52 were fat. There were significant differences in VFA and SFA between the two groups, with P values of 0.01 and 0.003, respectively. There was no significant difference in WHR, VF/SF and vBMD between the two groups. There was significant correlation between vBMD and VF/SF in young women (r=0.550, P=0.001). Conclusion The PBM of lumbar vertebrae was not correlated with BMI, WC, HC, VFA and SFA in young women, but significantly correlated with the ratio of VF / SF. Scientific slimming in young women would not reduce the BMD reserve.
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