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| 绝经后骨质疏松症不同中医证型与冠心病的相关性研究 |
| Correlation between TCM syndromes and coronary heart disease in postmenopausal osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2019.10.018 |
| 中文关键词: 中医证型 绝经后骨质疏松症 骨密度 冠心病 |
| 英文关键词:traditional Chinese medicine syndrome postmenopausal osteoporosis bone mineral density coronary heart disease |
| 基金项目:广东省中医药局基金项目（20172082） |
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| 中文摘要: |
| 目的 探讨女性绝经后骨质疏松症不同中医症型与冠心病的相关性。方法 选择2017年6月至2018年6月在我院就诊的214例绝经后中老年女性患者，收集一般临床资料和常规检验指标结果，对患者进行骨密度（bone mineral density，BMD）、冠脉CT检查，并与不同中医证型进行相关性分析。结果 气滞血瘀组患者腰1～4椎体（L1-L4）BMD值最低，与肾阳虚、肝肾阴虚、脾肾阳虚组比较差异有统计学意义（P＜0.05）；而冠心病的比率更高，与肾阳虚、肝肾阴虚、脾肾阳虚组比较差异有统计学意义（P＜0.05），并且多支血管病变比率更高。结论 绝经后女性气滞血瘀型骨质疏松的发生率更高，并与冠状动脉硬化发生及严重程度存在相关性；对于两者的协同治疗有重要意义。 |
| 英文摘要: |
| Objective To investigate the relationship between traditional Chinese medicine (TCM) syndromes and coronary heart disease (CHD) in postmenopausal osteoporosis. Methods A total of 214 patients who were diagnosed postmenopausal osteoporosis from June 2017 to June 2018 were enrolled in this study. Clinical characteristic of patients were recorded. All patients were examined by Dual-energy X-ray absorptiometry（DXA）and CT coronary angiography (CTCA), and the correlation analysis were made with different TCM syndrome types. Results The lowest bone mineral density (BMD) of the lumbar spine (L1-L4) was in the qi stagnation and blood stasis type, and the difference was statistically significant compared with the kidney Yang deficiency, liver and kidney Yin deficiency, and spleen and kidney Yang deficiency types (P<0.05). The incidence of coronary heart disease was increased in the qi stagnation and blood stasis type, and the difference was statistically significant compared with the kidney Yang deficiency, liver and kidney Yin deficiency, spleen and kidney Yang deficiency types (P<0.05), with higher rate of multivessel disease. Conclusion The incidence of postmenopausal women osteoporosis was higher in the qi stagnation and blood stasis type, correlated with the occurrence and severity of coronary heart disease, thus the collaborative treatment of osteoporosis and coronary heart disease in the qi stagnation syndrome group is of great significance. |
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