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| 椎体后凸成形术治疗580例老年性骨质疏松性椎体压缩性骨折疗效的影响因素分析 |
| Effect of percutaneous kyphoplasty on 580 cases osteoporotic vertebral compression fracture |
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| DOI：10.3969/j.issn.1006-7108.2019.10.022 |
| 中文关键词: 骨质疏松 椎体压缩性骨折 椎体后凸成形术 |
| 英文关键词:osteoporosis compression fracture of vertebral body percutaneous kyphoplasty |
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| 中文摘要: |
| 目的 分析椎体后凸成形术（percutaneous kyphoplasty，PKP )治疗老年性骨质疏松性椎体压缩性骨折的疗效并探讨其影响疗效的因素。方法 选择我院老年性骨质疏松性椎体压缩性骨折的580例患者行椎体后凸成形术，调取资料并记录与疗效相关的因素：年龄、性别、椎体压缩程度、楔形变角度、骨折椎体数量、骨折部位、单/双侧穿剌、骨水泥注人量、骨水泥椎间盘渗漏、规范抗骨质疏松治疗，并使用二分类Logistic冋归探讨这些因素与疗效之间存在的关系。结果 单变量因素分析椎体压 缩程度[OR = 2. 68 (2. 03~3. 24)，P<0.01]、骨折椎体数量[OR = 3. 54( 2. 87 ~4. 12)，P<0. 01 ]、骨折部位[OR = 4. 02(3. 34~67)，P<0,01]、骨水泥注入量[OR=2.52(2.01-2. 92)，P<0.05]、骨水泥椎间盘渗漏[OR = 1.98( 1.67~2. 42)，P<0.01 ]、规范抗骨质疏松治疗[OR = 2.70(2.31~3.22)，P<0.01]认为与术后疗效相关，进行多变量冋归分析，经多变量Logistic同归分析 (LR 法），骨折椎体数量[OR= 4.70(3.28~5. 61)，P = 0. 000]、骨水泥椎间盘渗漏[OR= 5.12(2. 07~8. 26)，P = 0. 000]、规范抗骨质疏松治疗[OR = 4. 40(2. 93~6. 71)，P = 0. 000]与椎体后凸成形术后疗效显著相关。结论 影响椎体后凸成形术疗效中， 骨折椎体数量、骨水泥椎间盘渗漏、规范抗骨质疏松治疗较其他因素与疗效关系更密切。 |
| 英文摘要: |
| Objective To analyze the curative effect of percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fracture and to explore the factors influencing the curative effect. Methods 580 cases of osteoporotic vertebral compression fracture in our hospital were treated with percutaneous kyphoplasty, the data were transferred and the related factors were recorded： age, sex, vertebral compression degree, wedge deformation angle, fracture vertebral body number, fracture site, unilateral /bilateral puncture, bone cement injection amount，bone cement intervertebral disc leakage, standard osteoporosis treatment, and use two classified logistic regression analysis to study the relationship between these factors and efficacy. Results Single variable factors analyzed vertebral compression degree [ OR = 2. 68(2. 03-3. 24) ,P<0. 01 ]，fracture vertebral body number [OR = 3. 54(2. 87-4. 12) , P<0. 01 ] , fracture site [OR = 4. 02(3. 34-4.67), P<0. 01 ] , Bone cement injection amount[ OR = 2. 52 (2. 01-2. 92)，P<0. 05] , bone cement intervertebral disc leakage [ OR = 1. 98 ( 1. 67—2. 42)，P<0. 01 ]，Standard osteoporosis treatment[ OR = 2. 70(2. 31-3. 22)，P<0. 01] . It is concluded that the multivariate regression analysis is related to the postoperative curative effect. The number of vertebral body [ OR = 4. 70(3. 28-5. 61)，P = 0. 000]，bone cement intervertebral disc leakage[ OR =12(2. 07-8. 26)，P = 0. 000]，and standard osteoporosis treatment [ OR = 4. 40( 2. 93-6. 71) , P = 0. 000] were significantly correlated with the postoperative effects of posterior convex plasty by multivariable logistic regression analysis (LR method ). Conclusion The number of fracture vertebral body, the leakage of bone cement intervertebral disc and the standard treatment of osteoporosis are more closely related to the curative effect of vertebral posterior convex plasty. |
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