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| 在中老年人群中2型糖尿病病程和FRAX评分之间相关性分析 |
| Relationship between the fracture risk by FRAX score and duration of diabetes in middle-aged and elder people with type 2 diabetes |
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| DOI：10.3969/j.issn.1006.7108.2019.11.007 |
| 中文关键词: 骨质疏松 FRAX 2型糖尿病 |
| 英文关键词:osteoporosis FRAX type 2 diabetes |
| 基金项目:江阴市卫计委科研项目面上项目(M201504） |
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| 中文摘要: |
| 目的 探讨FRAX评分在与糖尿病病程之间的关系。方法 选取278例糖尿病人群，并收集相关临床指标。通过FRAX公式计算2型糖尿病患者10年髋部骨折发生概率（PHF）和10年主要骨质疏松性骨折发生概率（PMOF）。研究2型糖尿病患者中FRAX与糖尿病病程之间的关系。结果 发现随着糖尿病病程的延长，L1-4、股骨颈骨密度均无明显改变（P>0.05），而随着病程的增长，PMOF、PHF水平之间有区别，差异有统计学意义，且随着病程的延长两者呈逐渐增大的趋势（P <0.05）。 结论 糖尿病病程与10年骨质疏松性骨折发生概率之间有密切相关性。 |
| 英文摘要: |
| Objective To evaluate the relationship between the fracture risk by FRAX score and duration of diabetes. Methods A total of 278 people with type 2 diabetes were enrolled and their clinical data were collected. We evaluate the 10-year probability of hip fracture (PHF) and a major osteoporotic fracture (PMOF) using the FRAX algorithm in order to investigate association between FRAX score and duration of diabetes. Results Bone mineral density of the lumbar spine (L1-4) and the femoral neck (FN) in DM group increased with increasing of duration of type 2 diabetes (P>0.05). However, with the increase of duration, there was gradually increasing trend in PMOF and PHF (P<0.05). Conclusion There is close correlation among PHF, PMOF, and duration in type 2 diabetes. |
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