| Objective To observe the effects of osteoporosis fracture history and complications on health-related quality of life (HRQOL). Methods This study was based on 5-year-data obtained from 2013 to 2018. Osteoporosis was diagnosed in 2078 survey participants according to their bone mineral density measurements using dual energy X-ray absorptiometry. According to the World Health Organization study group, T-scores at or above –1.0 are considered as normal, those between –1.0 and –2.5 as osteopenia, and those at or below –2.5 as osteoporosis. The EuroQol five-dimensional questionnaire (EQ-5D) index score was used to assess the QOL. Results Of 2078 patients diagnosed with osteoporosis, incidence of fracture was 11.02%. Wrist fractures were the most frequent, affecting 4.52% of the patients. The incidence between men and women was significantly different (P<0.001). The overall EQ-5D index score was 0.84±0.01 in patients with osteoporosis. Except of cancer, the EQ-5D index score was significantly lower in those with osteoarthritis, rheumatoid arthritis, hypertension, diabetes, chronic obstructive pulmonary disease, and cardiovascular events than those without any related diseases. Conclusion We found that low HRQOL is associated with previous spine fracture and complications in patients with osteoporosis. Multiple fracture experiences greatly deteriorate HRQOL in patients with osteoporosis. |