| Liver transplantation is a relatively mature organ transplantation technique. With the continuous development of liver transplantation and postoperative immunosuppressive technology, the postoperative survival rate of liver transplantation patients has been greatly improved. Overall, the quality of life of patients after liver transplantation is good, but recent studies have found that the incidence of postoperative osteoporosis and fractures in liver transplant patients is significantly increased. The occurrence of osteoporosis in postoperative patients is mainly related to the reduction of bone content before liver transplantation and the massive loss of bone after surgery. All liver transplant patients should be evaluated, preferably in the pre-transplant period or early post-transplantation, and evaluation should include metabolic factors that may lead to bone disease. All patients are recommended to measure bone mineral density, assess fracture risk, and conduct osteopathic management after liver transplantation accordingly. This review discusses bone mineral density changes and fracture incidence after liver transplantation, factors of osteoporosis caused by liver disease and transplantation, and management of osteoporosis before and after liver transplantation. |