绝经后女性骨密度和生活质量、睡眠质量及疲劳之间相关性研究
Correlation between bone mineral density and quality of life, sleep quality and fatigue in postmenopausal women
  
DOI:10.3969/j.issn.1006-7108.2019.12.018
中文关键词:  骨质疏松症  生活质量  睡眠质量  疲劳
英文关键词:osteoporosis  quality of life  quality of sleep  fatigue
基金项目:三亚市医疗科技创新项目(2016YM06)
作者单位
张秋彦 白曼莫* 海南省三亚市中医院海南 三亚? ??572000 
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中文摘要:
      目的 本研究旨在探讨绝经后妇女的生活质量(quality of life,QOL)、睡眠质量和疲劳水平与骨密度(bone mineral density,BMD)之间的关系。方法 本研究纳入113例无骨折的绝经后骨质疏松症(postmenopausal osteoporosis,PMO)患者,172例骨量减少患者和102例BMD正常的患者。疼痛、生活质量、睡眠质量和疲劳的严重程度使用视觉模拟量表(VAS)、欧洲骨质疏松症基金会QOL问卷(QUALEFFO-41)、匹兹堡睡眠质量指数(PSQI)和个人力量(CIS)问卷检查表评估。结果 在VAS和QUALEFFO-41总分方面,三组间差异无统计学意义 (P>0.05)。另一方面,与BMD正常组相比,PMQ和骨量减少组的PSQI和CIS总分比较差异具有统计学意义(分别为P = 0.015和0.007)。结论 QOL、睡眠质量和疲劳对PMO或骨量减少的女性影响显著。
英文摘要:
      Objectives This study was undertaken to examine the associations between quality of life (QOL), the quality of sleep and fatigue level and bone mineral density (BMD) in postmenopausal women. Methods In this study, 113 postmenopausal osteoporosis (PMO) subjects without fractures, 172 subjects with osteopenia and 102 subjects with normal BMD were included. The severity of pain, QOL, quality of sleep and fatigue were assessed using the visual analogue scale (VAS), the QOL Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41), the Pittsburgh Sleep Quality Index (PSQI) and the Checklist of Individual Strength (CIS) questionnaire. Results No statistically significant differences between the three groups were found in terms of VAS and QUALEFFO-41 total scores (P>0.05). On the other hand, PSQI and CIS total scores were significantly different in the PMO and osteopenia groups (P=0.015 and 0.007, respectively) compared to the group with normal BMD. Conclusions QOL, sleep quality and fatigue have a significant impact on women with PMO or osteopenia.
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