| Objective To investigate the prevalence of osteoporosis, bone mass change, and distribution of main clinical epidemiological features in men under 50 years old and premenopausal women with bone mineral density (BMD) scores lower than average level, and to provide evidence for the prevention and treatment of osteoporosis. Methods ①BMD of the lumbar vertebrae and the hip was detected using a HOLOGIC DEXA machine. BMD results and the clinical data of 2100 patients were analyzed based on A, B, C, and D age groups. ②WHO Asian diagnostic criteria for osteoporosis were applied. BMD score Z >–2.0 SD was normal and Z ≤–2.0 SD was below the average in the same age group. Results ①Among the 2100 cases, 80.14% (1683/2100) had BMD score within the range of the same age people, and 19.86% (417/2 100) had BMD score lower than the range of the same age people. In those who had lower BMD, 214 cases were males (24.24%) and 203 cases were females (16.68%, P<0.05). ②In those men who were less than 50 years old and had lower BMD score, 61 cases had malnutrition, 43 cases had functional kidney disease, 33 cases had rheumatoid disease, 33 cases had diabetes, 22 cases had surgery, and 72 cases had osteoporosis. In premenopausal women who had lower BMD score, 62 cases had malnutrition, 47 cases had surgery, 31 cases had functional kidney disease, 25 cases had thyroid disease, 23 cases had SLE, and 65 cases had osteoporosis. Conclusion The prevalent rate of low BMD is higher in men less than 50 years old than in premenopausal women (P < 0.05). The characteristics of bone mass change in the lumbar vertebrae and the hip and main clinical epidemiological features are different between different genders. The active prevention should be carried out based on the clinical epidemiological features. |