| Objective To use FRAX tools to predict the risk of osteoporotic fracture in patients with type 2 diabetes mellitus (T2DM) in western Guangxi, and to evaluate the application value and population applicability of FRAX tools in this region. Methods From January 2015 to April 2015, 198 cases of type 2 diabetes mellitus (T2DM) patients from western Guangxi were screened, and 67 cases were selected according to the inclusion criteria. Relevant clinical data of fracture risk factors and bone mineral density measurement T-score were collected. According to the ultrasonic bone mineral density T-score, the selected subjects were divided into 3 groups: 37 cases with T-score ≥–1 were defined as normal bone density group, 22 cases with –2.5< T-score <–1 were considered as low bone density group, and 8 cases with T-score ≤–2.5 were considered as osteoporosis group. Groups were divided into male group (n = 38) and female group (n = 29) according to gender. According to BMI, they were divided into normal and lean group, overweight group and obese group. The candidates were divided into four groups according to their age (the group range was 10 years, 40 years was the lower limit, and 79 years was the upper limit): (40-49) years old, (50-59) years old, (60-69) years old, and (70-79) years old. The incidence of major osteoporotic and hip fractures over a 10-year period was estimated by using FRAX and compared between groups. Results There were significant differences in major osteoporotic fracture rate (MOF), risk rate of hip fracture (HF) and body weight standard BMI among T2DM patients with different bone mineral density (T-score) in western Guangxi (P<0.01). HF differed in different BMI (P<0.05), while MOF was different by sex (P<0.05) and age (P<0.01). In addition, BMI and T-score were negatively correlated with fracture rate and had differences (P<0.01). Conclusion FRAX score was correlated with BMI and BMD T-score in patients with T2DM in western Guangxi, and the fracture risk of women aged 60~69 was higher than that of men. |