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| 绝经后医务人员骨密度与椎体骨折的横向研究 |
| Cross-sectional study of bone mineral density and vertebral fracture in the medical postmenopausal women with a single center in Guangzhou |
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| DOI：10.3969/j.issn.1006-7108.2020.08.009 |
| 中文关键词: 医务人员 绝经后女性 骨密度 椎体骨折 |
| 英文关键词:medical staff postmenopausal women bone mineral disenty vertebral fracture |
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| 中文摘要: |
| 目的 通过横向研究探讨绝经后医务人员骨密度与椎体骨折的相互关系。方法 从单中心医务人员中，随机抽取216名绝经后女性，通过双能X线吸光测定仪检测其骨密度，运用Genant半定量法评估椎体骨折，分析骨密度与骨质疏松性骨折、椎体骨折的畸形程度以及EQ-5D评分的关系。结果 绝经后医务人员椎体骨密度的正常组、骨量减少组及骨质疏松组分别占27%、35%、38%；随着骨密度T值的降低，正常组（T≥-1.0）、骨量减少组（-2.5＜T＜-1.0）和骨质疏松组（T≤-2.5）的椎体骨质疏松性骨折患病率明显升高（P<0.05），分别为28%、42%和53%；椎体骨折组（无论有/无临床症状）的骨密度明显低于无骨折组（P<0.01）；椎体骨折畸形程度越重，其骨密度越低（P<0.01），躯体伸展程度、日常活动、疼痛或舒适度的EQ-5D评分亦越低（P<0.05）。结论 绝经后医务人员随着骨密度的降低，骨质疏松和椎体骨折的患病率增加，生活质量亦降低。 |
| 英文摘要: |
| Objective To analyze the relationship between bone mineral density (BMD) and vertebral fracture in the medical postmenopausal women through a cross-sectional study. Methods A total of 216 postmenopausal women from the medical staff in a single center was entered randomly. The measurement for BMD was used by dual energy X-ray absorptiometry. Vertebral fracture was evaluated by a semi-quantitative method using the Genant,s method. The relationship between BMD and osteoporotic fracture, a degree of deformity in vertebral fracture and EQ-5D was analyzed. Results The distribution of the normal, osteopenia and osteoporosis group in the medical postmenopausal women were 27%, 35% and 38%. The prevalence of the normal(T≥-1.0), osteopenia(-2.5＜T＜-1.0) and osteoporosis(T≤-2.5) group were decrease significantly with the T-scores increases(P<0.05); They were 28%, 42% and 53% respectively. BMD in subjects with symptomatic or asymptomatic vertebral fracture were significantly lower than those without fracture(P<0.01). The BMD was significantly lower with more severe degree of deformity in vertebral fracture(P<0.01) and lower scores in mobility, usual activities and pain/discomfort of the EQ-5D(P<0.05).Conclusion In the medical postmenopausal women, the prevalence of osteoporosis and vertebral fracture increase and quality of life decrease with lower BMD. |
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