| Objective To investigate the effect of physiological factors on the prevalence of osteoporosis and bone mineral density (BMD) in postmenopausal women in Guangzhou communities, and to provide further evidence for the prevention of osteoporosis in postmenopausal women. Methods Basic data (including general information, menstrual history, fertility history, previous history, surgical history, etc.) of the subjects were investigated with field questionnaire. BMD of the lumbar spine and left hip of 1199 postmenopausal women were measured using the dual-energy X-ray absorptiometry (United States). Results Among the 814 postmenopausal women, 300 cases (36.9%) had osteoporosis in the lumbar spine. The incidence of hip osteoporosis was 38.3% in 312 cases. Among women who had been menopausal for 10 years, the lower the BMD at the later age of menarche, the higher the risk of osteoporosis. Among postmenopausal women aged 55-65, the lower the BMD at the early age of menopause, the higher the risk of osteoporosis. The shorter the duration of menstruation, the lower the BMD and the higher the risk of osteoporosis. Conclusion The prevalence of osteoporosis is higher in postmenopausal women in Guangzhou communities. The incidence of osteoporosis significantly increased in women with late menarche, early menopause, and the age of menstruation. Therefore, early screening, diagnosis, and treatment are recommended. BMD value of the hip is sensitive in the assessment of osteoporosis. BMD measurement of the hip should be the first choice of measurement site. |