| Objective To evaluate the correlation between the degree of lumbar osteoporosis and bone mineral density (BMD) in women measured using VIBE-Dixon technology. Methods One hundred and twenty-one healthy female subjects were divided into 21-30 years old group (n=17), 31-40 years old group (n=11), 41-50 years old group (n=24), 51-60 years old group (n=63), and 61-70 years old group (n=6). BMD of the L1-L4 vertebral body was measured using dual-energy X-ray absorptiometry (DXA). The bone marrow fat fraction of L1-L4 vertebral body was measured using VIBE-Dixon technique. The differences of bone marrow fat fraction were compared among different groups. Meanwhile, the correlations between bone marrow fat fraction and BMD, between bone marrow fat fraction and age were analyzed, respectively. In addition, the correlation analysis on BMD, bone marrow fat fraction, and menopausal duration was performed. Results The differences among the groups were statistically significant (F value: 14.541, P<0.001). There was a correlation between bone marrow fat fraction and age (r=0.659, P<0.001). BMD decreased with the increase of fat fraction. With the prolongation of menopause age, BMD decreased and bone marrow fat content increased. Conclusion VIBE-Dixon quantitatively measures the fat content of lumbar vertebra and indirectly evaluates the degree of osteoporosis. It is correlated with the DXA results. |