QCT与DXA在藏族、汉族骨密度评估中的差异
The difference of bone mineral density measurement between lumbar quantitative CT and DXA in Tibetans and Han nationality
  
DOI:10.3969/j.issn.1006-7108.2020.09.019
中文关键词:  定量CT  骨密度  藏族
英文关键词:QCT  BMD  Tibetans
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郭彦宏1 邬云红1 王溯源1 何万林2 李相位2 黄伦浪1 李明霞1 程晓光3* 1. 西藏自治区人民政府驻成都办事处医院内分泌科四川 成都 610000 2. 西藏自治区人民政府驻成都办事处医院放射科四川 成都 610000 3. 北京积水潭医院放射科北京100035 
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中文摘要:
      目的 比较QCT与DXA在藏族、汉族患者骨密度评估中的差异,探讨DXA、QCT在藏族骨质疏松患者中的临床价值。方法 收集2018年12月至2019年9月期间在我院同时行腰椎DXA及腰椎QCT检查的患者一般诊疗信息及DXA、QCT检查结果,同时有经验丰富的影像科医师通过腰椎CT影像对椎体及相近附件行影像学诊断。正态性分布的计量资料以均数±标准差表示,组间比较独立样本t检验,率的比较采用Fisher确切概率法。结果 藏族平均腰椎DXA T值高于汉族(?0.19±2.44 vs ?1.17±1.40,P<0.05),但藏、汉两族QCT骨量差异无统计学意义(71.51±24.10 mg/cm3 vs 75.31±25.01mg/cm3)。在藏族、汉族患者中QCT检出骨质疏松的例数均多于DXA,差异有统计学意义(P=0.004);慢性肾脏疾病患者DXA表现为高T值同时QCT可为正常骨量。结论 对于体型肥胖、合并椎体退行性变或慢性肾脏疾病的患者应选用QCT评估其骨密度,较DXA,QCT能更为准确地评估藏族患者骨密度。
英文摘要:
      Objective To compare the difference of bone mineral density measurement between lumbar quantitative CT (QCT) and DXA in Tibetans and Han nationality, and to discuss clinic value of QCT and DXA in Tibetan patients. Methods General character information and DXA, QCT reports were collected at Hospital of Chengdu Office of People's Government of Tibetan from December 2018 to September 2019. The imaging diagnosis of these patients was performed by experienced radiologists through lumbar CT images. Normal distribution data were showed as mean and standard deviation. The t test was used for the comparison of independent samples between the groups. Fisher's exact probability calculation method was used to compare the sample rate between the groups. Results The average DXA T value in Tibetan patients was higher than that in Han patients (?0.19±2.44 vs. ?1.17±1.40, P<0.05). However, there was no significant difference of BMD between Tibetan and Han patients measured with QCT (71.51±24.10 vs. 75.31±25.01mg/cc). The number of cases of osteoporosis detected with QCT was more than that with DXA, and the difference was statistically significant (P=0.004). In patients with chronic kidney disease, DXA showed high T values while QCT showed normal bone mass. Conclusion For patients with obesity, vertebral degeneration, or chronic kidney disease, QCT should be used to evaluate their BMD. BMD is more accurately evaluated by QCT than by DXA in Tibetan patients.
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