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| 南京地区低能量骨折老年患者存在维生素 D缺乏的回顾性研究 |
| Vitamin D deficiency in elderly patients with distal radius fractures and hip fractures in Nanjing area: A retrospective study |
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| DOI：10.3969/j.issn.1006-7108.2020.09.021 |
| 中文关键词: 低能量骨折 桡骨远端骨折 髋部骨折 维生素D 南京 |
| 英文关键词:low-energy fracture, distal radius fracture, hip fracture, vitamin D, Nanjing |
| 基金项目:国家自然科学基金（甲状旁腺素相关肽在促进骨折愈合中的作用和机制研究）（81271997） |
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| 中文摘要: |
| 目的 研究评估南京地区老年低能量骨折（桡骨远端和髋部骨折）患者维生素D[Vitamin D,Vit D; 25 (OH) D]水平，以及补充活性Vitamin D是否可以有效提高血清25 (OH) D水平。方法 回顾性研究南京鼓楼医院骨折联络服务（FLS）病例中90名老年（≥65岁）患者，桡骨远端骨折49名，髋部骨折41名，受伤后均给予口服活性Vitamin D治疗。分析受伤时和伤后4周的25 (OH) D水平。 结果 所有桡骨远端骨折的患者，受伤时血清25 (OH) D水平为14.83 ng/mL，伤后4周为21.23 ng/mL；在髋部骨折患者受伤时 血清25 (OH) D水平为9.92 ng/mL，伤后4周为18.96 ng/mL。结论 桡骨远端以及髋部骨折老年患者的25 (OH) D水平较低，有可能使肌肉力量下降导致跌倒风险增加，Vitamin D的补充可以有效提高血清25 (OH) D水平。 |
| 英文摘要: |
| Objective To evaluate the vitamin D (Vit D, 25 (OH) D) levels in elderly patients with low energy fractures of the distal radius or hip fractures in Nanjing, and the effect vitamin D supplementation on serum 25 (OH) D level. Methods A retrospective study of 90 elderly (≥65 years old) patients with fracture liaison service (FLS) in Nanjing Drum Tower Hospital, including 49 distal radius fractures and 41 hip fractures was conducted. The patients received oral vitamin D after injury. Serum 25 (OH) D levels were analyzed at the time of injury, and 4 weeks after the injury. Results In all patients with distal radius fractures (n = 49), serum 25 (OH) D level was 14.83 ng / mL at the time of injury and 21.23 ng / mL at 4 weeks after injury, respectively. Serum 25 (OH) D levels were 9.92 ng / mL at the time of injury in hip fracture patients (N = 49) and 18.96 ng / mL at 4 weeks after injury. Conclusion Vitamin D levels were lower in elderly patients with distal radius or hip fractures. Low vitamin D levels may decrease muscle strength and increase the risk of falls. Vitamin D supplementation can effectively increase serum 25 (OH) D levels. |
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