| Objective To analyze the potential influencing factors of bone mineral density(BMD) in gestational diabetes mellitus (GDM) patients during the second trimester of pregnancy, and to provide reference for clinical intervention programs of BMD in pregnant women. Methods According to the purpose of the study, 200 pregnant women with diabetes mellitus from 24 to 26 weeks of gestation were investigated by questionnaires on diet, living habits, family history of osteoporosis and dietary supplements, and their height, weight, bone mineral density and biochemical indicators were examined. Results The intake of dark green vegetables in osteoporosis group was higher than that in normal bone group (P < 0.05), while the intake of light green vegetables, red-orange-yellow vegetables, milk, legumes and complex nutrients in osteoporosis group was lower than that in normal bone group (P < 0.05).The results of multivariate logistic regression analysis were the same as former results. The levels of fasting blood sugar, glycosylated hemoglobin and alkaline phosphatase in osteoporosis group were higher than those in normal bone group (P < 0.05), while those in white bone group (P < 0.05). Protein and retinol binding protein were lower than those in normal bone GDM group (P < 0.05). Conclusion Light green vegetables, red and orange vegetables, milk and soybean products, the intake of complex nutrients all can protect the bone mineral density of patients with GDM in the second trimester., while excessive intake of dark green vegetables may have a negative effect on bone mineral density of GDM patients in the second trimester. |