| Objective To analyze the relationship between serum 25-hydroxyvitamin D(25(OH)D) levels and metabolic syndrome (MS) and its components in newly diagnosed male patients with type 2 diabetes mellitus (T2DM). Methods 203 newly diagnosed male T2DM patients admitted to the department of endocrinology, affiliated hospital of zunyi medical university from March 2018 to June 2019 and 42 healthy male control group (NC group) in the same period were collected. The diabetic patients were divided into T2DM+MS group (n=122) and T2DM+ non-MS group (n=81) according to whether MS was present or not. Another according to the number of MS diagnosis standard divided into T2DM group (simple diabetes group), T2DM+1 group (except abnormal blood glucose plus a component), T2DM+2 group (except abnormal blood glucose plus two components), T2DM+3 group(except abnormal blood glucose plus three components), T2DM+4 group (has all the components of the MS).WC, BMI, SBP, DBP, FBG, HbAlc, HOMA-IR, TG, TC, LDL-C, HDL-C and 25 (OH) D levels were analyzed. Results Compared with the NC group, the serum levels of 25(OH)D in the T2DM+MS group and the T2DM+ non-MS group was significantly decreased(P<0.05). Serum 25(OH)D levels in the T2DM+MS group decreased significantly (P<0.05). Serum 25 (OH)D levels in NC group, T2DM group, T2DM+1 group, T2DM+2 group, T2DM+3 group, and T2DM+4 group decreased gradually, with statistically significant differences (P<0.05). The levels of serum 25(OH)D were negatively correlated with WC, BMI, SBP, DBP, HOMA-IR, FBG, TG, TC and LDL-C, and positively correlated with HDL-C (P<0.05). Conclusion Serum vitamin D levels may play a role in the development of metabolic syndrome in newly diagnosed male T2DM patients. Low levels of vitamin D were associated with an increase in the number of MS components. |